Asian Journal of Research in Pharmaceutical Sciences

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Formulation and Evaluation of Buccal Disintegrating Tablet of Anticonvulsant Drug


Affiliations
1 Vidyaniketan College of Pharmacy, Anjangaon Surji-444705, Maharashtra, India
2 Shri Sant Gajanan Maharaj College of Pharmacy Buldhana Maharastra,, India
     

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Oral and Buccal delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. To troubleshoot such problems a new dosage form known as Buccal and orally disintegrating tablet, has been developed which rapidly disintegrate and dissolve in saliva and then easily swallowed without need of water which is a major benefit over than conventional dosage form. In addition, patients suffering from dysphasia, motion sickness, repeated emesis and mental disorders prefer such preparation because they cannot swallow large quantity of water. the immediate release of medication and for instant release at desire location in which the drug is absorbed distributer and easily metabolized. e.g. To prepare and characterize buccal tablets of Gabapentin using different super disintegrants such as Cross povidon, PVP K30, Micro crystalline cellulose. This types of formulation of improving solubility of drug and development of Buccal drug delivery system.

Keywords

Buccal disintegrating tablet of gabapentine
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  • Formulation and Evaluation of Buccal Disintegrating Tablet of Anticonvulsant Drug

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Authors

Akshay M Akotakar
Vidyaniketan College of Pharmacy, Anjangaon Surji-444705, Maharashtra, India
Ashwini A Zanke
Shri Sant Gajanan Maharaj College of Pharmacy Buldhana Maharastra,, India
Ananta B Ghonge
Shri Sant Gajanan Maharaj College of Pharmacy Buldhana Maharastra,, India

Abstract


Oral and Buccal delivery is currently the gold standard in the pharmaceutical industry where it is regarded as the safest, most convenient and most economical method of drug delivery having the highest patient compliance. To troubleshoot such problems a new dosage form known as Buccal and orally disintegrating tablet, has been developed which rapidly disintegrate and dissolve in saliva and then easily swallowed without need of water which is a major benefit over than conventional dosage form. In addition, patients suffering from dysphasia, motion sickness, repeated emesis and mental disorders prefer such preparation because they cannot swallow large quantity of water. the immediate release of medication and for instant release at desire location in which the drug is absorbed distributer and easily metabolized. e.g. To prepare and characterize buccal tablets of Gabapentin using different super disintegrants such as Cross povidon, PVP K30, Micro crystalline cellulose. This types of formulation of improving solubility of drug and development of Buccal drug delivery system.

Keywords


Buccal disintegrating tablet of gabapentine

References