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Discovery of a new Drug: A Fundamental Review Rakesh Kumar
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The discovery of a new drug started with drug’s compounds derived from natural sources (animals, plants, microorganisms or marine sources) or compounds are synthesized in the laboratory. The Researchers insight into a disease process and design a product to stop or reverse the effects of the disease. Now study the Existing treatments followed by new technologies make drug to target specific sites. Once researchers identify a promising compound then a series of experiments conducted. How it is absorbed, distributed, metabolized and excreted, best dose, best way to deliver, side effects, effectiveness and mechanism of action. q
Keywords
Drug, target, lead compound, lead optimization, preclinical and clinical trials, pharmacological activities, drug delivery, side effects, etc.
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- Definition and classification of Drug or Pharmaceutical Regulatory aspects of drug approval Accessed 30 Dec 2013.
- IR McWhinney; Health and disease: problems of definition, Canadian Medical Association Journal, 2007, 136 (8): 815.
- KD Tripathi; Pharmacological classification of drugs with doses and preparations, 4th edition, 2006.
- Aarti Sharma, et al., Journal of Pharmacy and Bioallied Sciences. J. Pharm. Bioallied Sci., 2010, 2(4): 290–299. [drug: Development trends and strategies]
- Gareth Thomas; Fundamentals of Medicinal Chemistry, Wiley Pub, 2003.
- V. Alagarsamy; Text book of Medicinal Chemistry, Vol I & Vol II, 2010.
- Andrew Dewis; The Handbook of Medicinal Chemistry: Principles and Practices, 2015.
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