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Comparative Analysis of Major Alkaloids in Piper Species Traded as 'Pippali' in South Indian Markets:Absence of the Chief Known Constituent - Piperine in Selected Samples


Affiliations
1 School of Life Sciences, Institute of Transdisciplinary Health Sciences and Technology, Foundation for Revitalisation of Local Health Traditions (FRLHT), 74/2, Jarakabande Kaval Attur PO, Yelahanka, Bengaluru 560 064, India
2 Department of Forestry, North Eastern Regional Institute of Science and Technology (NERIST), Nirjuli 791 109, India
 

The major alkaloids in piper species traded in South Indian markets as the Ayurvedic drug, Pippali, have been studied using a rapid HPLC-based method. Piper longum is the accepted botanical source of Pippali. Bengaluru and Chennai markets contained mixtures of closely related species, Piper peepuloides and Piper sylvaticum. Chemical analysis showed that these sam-ples do not contain the alkaloid piperine present in Piper longum fruits. Market samples from Trissur were identified as Piper longum and piperine was detected as one of the major alkaloids. All the samples contained pellitorine, another alkaloid reported in most peppers of the genus Piper. The two types of Pippali can therefore be easily differentiated on the basis of their HPLC profiles.

Keywords

Alkaloids, Ayurvedic Drug, HPLC, Pippali, Piper longum, Piperine.
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  • Comparative Analysis of Major Alkaloids in Piper Species Traded as 'Pippali' in South Indian Markets:Absence of the Chief Known Constituent - Piperine in Selected Samples

Abstract Views: 439  |  PDF Views: 118

Authors

Vijayalakshmi Babu
School of Life Sciences, Institute of Transdisciplinary Health Sciences and Technology, Foundation for Revitalisation of Local Health Traditions (FRLHT), 74/2, Jarakabande Kaval Attur PO, Yelahanka, Bengaluru 560 064, India
Sandhya Kumari Singh
School of Life Sciences, Institute of Transdisciplinary Health Sciences and Technology, Foundation for Revitalisation of Local Health Traditions (FRLHT), 74/2, Jarakabande Kaval Attur PO, Yelahanka, Bengaluru 560 064, India
Padma Venkatasubramanian
School of Life Sciences, Institute of Transdisciplinary Health Sciences and Technology, Foundation for Revitalisation of Local Health Traditions (FRLHT), 74/2, Jarakabande Kaval Attur PO, Yelahanka, Bengaluru 560 064, India
Padma Raj Gajurel
Department of Forestry, North Eastern Regional Institute of Science and Technology (NERIST), Nirjuli 791 109, India

Abstract


The major alkaloids in piper species traded in South Indian markets as the Ayurvedic drug, Pippali, have been studied using a rapid HPLC-based method. Piper longum is the accepted botanical source of Pippali. Bengaluru and Chennai markets contained mixtures of closely related species, Piper peepuloides and Piper sylvaticum. Chemical analysis showed that these sam-ples do not contain the alkaloid piperine present in Piper longum fruits. Market samples from Trissur were identified as Piper longum and piperine was detected as one of the major alkaloids. All the samples contained pellitorine, another alkaloid reported in most peppers of the genus Piper. The two types of Pippali can therefore be easily differentiated on the basis of their HPLC profiles.

Keywords


Alkaloids, Ayurvedic Drug, HPLC, Pippali, Piper longum, Piperine.

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DOI: https://doi.org/10.18520/cs%2Fv111%2Fi9%2F1507-1510