Current Science

Open Access Open Access  Restricted Access Subscription Access

Presumptive Case of Ciguatera Fish Poisoning in Mangalore, India


Affiliations
1 Department of Fisheries Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences, University, College of Fisheries, Mangalore 575 002, India
 

Ciguatera fish poisoning (CFP) occurs when humans ingest fishes contaminated with ciguatoxins (CTXs). Two individuals developed suspected ciguatera poisoning after consuming unknown fish purchased from a local market in Mangalore, India. DNA barcoding confirmed the fish under study to be Lutjanus bohar. A mouse bioassay study detected high levels of CTX in the implicated fish. Mice injected with toxin showed typical symptoms of CTX poisoning. To the best of our knowledge, this is a first case report of CFP due to consumption of L. bohar in India.

Keywords

Ciguatera Fish Poisoning, Cytochrome Oxidase, DNA Barcoding, Lutjanus bohar, Mouse Bioassay.
User
Notifications
Font Size

  • Abraham, A., Jester, E. L. E., Granade, H. R., Plakas, S. M. and Dickey, R. W., Caribbean ciguatoxin profile in raw and cooked fish implicated in ciguatera. Food Chem., 2012, 131, 192–198.

  • Yasumoto, T., Chemistry, etiology and food chain dynamics of marine toxins. Proc. Jpn. Acad. Ser. B Phys. Biol. Sci., 2005, 81, 43–51.

  • Johnson, R. and Jong, E. C., Ciguatera: Caribbean and IndoPacific fish poisoning. West J. Med., 1983, 138, 872–874.

  • Dickey, R. W. and Plakas, S. M., Ciguatera: a public health perspective. Toxicon, 2010, 56, 123–136.

  • Friedman, M. et al., Ciguatera fish poisoning: treatment, prevention and management. Mar. Drugs, 2008, 6, 456–479.

  • Farstad, D. J. and Chow, T., A brief case report and review of ciguatera poisoning. Wild Environ. Med., 2001, 12, 263–269.

  • Bienfang, P. et al., Ciguatera: the detection of neurotoxins in carnivorous reef fish from the coast of Cameroon, West Africa. Afr. J. Mar. Sci., 2008, 30, 533–540.

  • Villareal, T., Hanson, S., Qualia, S., Jester, E., Granade, H. and Dickey, R., Petroleum production platforms as sites for the expansion of ciguatera in the northwestern Gulf of Mexico. Harmful Algae, 2007, 6, 253–259.

  • Lewis, R. J., Ciguatera management. SPC Live Reef Fish Inf. Bull., 2000, 7, 11–13.

  • Hokama, Y., Ciguatera fish poisoning. J. Clin. Lab. Anal., 1988, 2, 44–50.

  • Lehane, L. and Lewis, R. J., Ciguatera: recent advances but the risk remains. Int. J. Food Microbiol., 2000, 61, 91–125.

  • Lewis, R. J., Ciguatera: Australian perspectives on a global problem. Toxicon, 2006, 48, 799–809.

  • Wong, C. K., Hung, P., Lee, K. L. H. and Kam, K. M., Study of an outbreak of ciguatera fish poisoning in Hong Kong. Toxicon, 2005, 46, 563–571.

  • Caillaud, A. et al., Update on methodologies available for ciguatoxin determination: perspectives to confront the onset of ciguatera fish poisoning in Europe. Mar. Drugs, 2010, 8, 1838–1907.

  • Blythe, D., Fleming, L., Ram Ayyar, D., De Sylva, D., Baden, D. and Schrank, K., Mannitol therapy for acute and chronic ciguatera fish poisoning. Mere. Qld Museum, Brisbane, 1994, 34, 465–470.

  • Sambrook, J., Fritsch, E. F. and Maniatis, T., Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory Press, New York, 1989.

  • Ward, R. D., Zemlak, T. S., Innes, B. H., Last, P. R. and Hebert, P. D. N., DNA barcoding Australia’s fish species. Philos. Trans. R. Soc. London, B, Biol. Sci., 2005, 360, 1847–1857.

  • Palumbi, S. R., Nucleic acids II: the polymerase chain reaction. In Molecular Systematics (eds Hillis, D. and Moritz, C.), Sinauer, Sunderland, 1996, pp. 205–247.

  • Thompson, J. D., Gibson, T. J., Plewniak, F., Jeanmougin, F. and Higgins, D. G., The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucl. Acids Res., 1997, 25, 4876–4882.

  • Tamura, K., Dudley, J., Nei, M. and Kumar, S., MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0. Mol. Biol. Evol., 2007, 24, 1596–1599.

  • Lewis, R. J., Detection of toxins associated with ciguatera fish poisoning. In Manual on Harmful Marine Microalgae (eds Hallegraeff, G. M. et al.), IOC Manuals and Guides, No. 33. UNESCO, France, 2003, pp. 267–277.

  • Lewis, R. J., Ciguatoxins are potent ichthyotoxins. Toxicon, 1992, 30, 207–211.

  • Maralit, B. A., Aguila, R. D., Ventolero, M. F. H., Perez, S. K. L., Willette, D. A. and Santos, M. D., Detection of mislabeled commercial fishery by-products in the Philippines using DNA barcodes and its implications to food traceability and safety. Food Control, 2013, 33, 119–125.

  • Lianming, Z., Jinru, H., Yuanshao, L., Wenqing, C. and Wenjing, Z., 16S rRNA is a better choice than COI for DNA barcoding hydrozoans in the coastal waters of China. Acta Oceanol. Sin., 2014, 3, 55–76.

  • www.fishbase.org/summary/Lutjanus-bohar

  • Hamilton, B., Hurbungs, M., Vernoux, J. P., Jones, A. and Lewis, R. J., Isolation and characterization of Indian Ocean ciguatoxin. Toxicon, 2002, 40, 685–693.

  • Rongo, T. and van Woesik, R., Ciguatera poisoning in Rarotonga, Southern Cook Islands. Harmful Algae, 2011, 10, 345–355.

  • Wong, C. K., Hung, P. and Lo, J. Y. C., Ciguatera fish poisoning in Hong Kong. A 10-year perspective on the class of ciguatoxins. Toxicon, 2014, 86, 96–106.

  • Oshiro, N. et al., Ciguatera incidence and fish toxicity in Okinawa, Japan. Toxicon, 2010, 56, 656–661.

  • Centre for Food Safety, Seasonal food safety tips – prevention of ciguatera fish poisoning start with choosing coral reef fish carefully, 2010.

  • Lucas, R. E., Lewis, R. J. and Taylor, J. M., Pacific ciguatoxin-1 associated with a large common-source outbreak of ciguatera in East Arnhem Land, Nat. Toxins, 1997, 5, 136–140.


Abstract Views: 339

PDF Views: 117




  • Presumptive Case of Ciguatera Fish Poisoning in Mangalore, India

Abstract Views: 339  |  PDF Views: 117

Authors

Moger Rajeish
Department of Fisheries Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences, University, College of Fisheries, Mangalore 575 002, India
Malathi Shekar
Department of Fisheries Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences, University, College of Fisheries, Mangalore 575 002, India
Hoovinahalli Nataraju Madhushree
Department of Fisheries Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences, University, College of Fisheries, Mangalore 575 002, India
Moleyur Nagarajappa Venugopal
Department of Fisheries Microbiology, Karnataka Veterinary, Animal and Fisheries Sciences, University, College of Fisheries, Mangalore 575 002, India

Abstract


Ciguatera fish poisoning (CFP) occurs when humans ingest fishes contaminated with ciguatoxins (CTXs). Two individuals developed suspected ciguatera poisoning after consuming unknown fish purchased from a local market in Mangalore, India. DNA barcoding confirmed the fish under study to be Lutjanus bohar. A mouse bioassay study detected high levels of CTX in the implicated fish. Mice injected with toxin showed typical symptoms of CTX poisoning. To the best of our knowledge, this is a first case report of CFP due to consumption of L. bohar in India.

Keywords


Ciguatera Fish Poisoning, Cytochrome Oxidase, DNA Barcoding, Lutjanus bohar, Mouse Bioassay.

References





DOI: https://doi.org/10.18520/cs%2Fv111%2Fi9%2F1543-1547