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Genetically modified (GM) cotton fortified with cry1Ac (crystal 1Ac) gene derived from the soil bacterium Bacillus thuringiensis (Bt), commonly known as Bt-cotton, was approved in 2002 for commercial cultivation in India. The Cry1Ac protein expressed in Bt-cotton is toxic to the three major cotton bollworms: the American bollworm, Helicoverpa armigera (Hübner) (Lepidoptera:Noctuidae), pink bollworm Pectinophora gossypiella (Saunders) (Lepidoptera:Gelechiidae) and spotted bollworms Earias vittella (Fabricius) (Lepidoptera:Noctuidae) and Earias insulana (Boisduval) (Lepidoptera:Noctuidae).
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