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It is a well accepted fact that chemical transformations can occur in solid, liquid and gaseous matrix; however, liquid matrix (solvent) dominates due to certain distinct multi-dimensional advantages especially at molecular level, making it a versatile tool for industrial manufacturing processes. It has been estimated that 28-million metric tonnes (MMT) of organic solvents are commercialized globally for different industrial purposes, majority of which get utilized in chemical and pharmaceutical manufacturing.
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