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Directed Evolution–Bringing the Power of Evolution to the Laboratory:2018 Nobel Prize in Chemistry


Affiliations
1 Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone, Faridabad 121 001, India
2 International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110 067, India
 

The 2018 Nobel Prize in Chemistry has been awarded to Frances H. Arnold, George P. Smith and Gregory P. Winter for harnessing the power of Darwinian evolution into the laboratory. As rightly mentioned by Claes Gustafsson, Chair of the Nobel Committee for Chemistry during the award announcement, ‘Our laureates have applied the principles of Charles Darwin in the test tubes, and used this approach to develop new types of chemicals for the greatest benefit of humankind’. This year’s Prize is dedicated to methods that create new molecules using the biosynthetic machinery of nature: directed evolution for making new enzymes and phage display for therapeutic antibodies.
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  • Directed Evolution–Bringing the Power of Evolution to the Laboratory:2018 Nobel Prize in Chemistry

Abstract Views: 427  |  PDF Views: 114

Authors

Sheenam Verma
Regional Centre for Biotechnology, NCR Biotech Science Cluster, 3rd Milestone, Faridabad 121 001, India
Dinakar M. Salunke
International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110 067, India

Abstract


The 2018 Nobel Prize in Chemistry has been awarded to Frances H. Arnold, George P. Smith and Gregory P. Winter for harnessing the power of Darwinian evolution into the laboratory. As rightly mentioned by Claes Gustafsson, Chair of the Nobel Committee for Chemistry during the award announcement, ‘Our laureates have applied the principles of Charles Darwin in the test tubes, and used this approach to develop new types of chemicals for the greatest benefit of humankind’. This year’s Prize is dedicated to methods that create new molecules using the biosynthetic machinery of nature: directed evolution for making new enzymes and phage display for therapeutic antibodies.

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DOI: https://doi.org/10.18520/cs%2Fv115%2Fi9%2F1627-1630