The Annual Review of Biophysics 2018, edited by Ken Dill of Stony Brook University, is part of a series published every year since 1972. Each volume in the series combines reviews of those developments in biophysics that have attracted attention in the recent past. The only requirement placed on the contributions, apart from the fact that they should be reasonably current, is that they must represent areas where physics and biology speak to each other. At 677 pages this year, the hard-back version of this book is weighty in every sense of the word.
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