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A department that is 100 not out! This is the best way to describe the Department of Biochemistry at IISc which is reminiscing into the past and looking into the future. Established on 16 February 1921, the department celebrated its Golden Jubilee and Platinum Jubilee in 1971 and 1996 respectively in the iconic building located in Tala Marg (see cover page). The centenary will be celebrated in the newly constructed Biological Sciences building in which the department occupies the first floor. I consider it a privilege to be the Chairperson of this department in its centennial year and write this article that provides a glimpse of various research activities of the department for the past 100 years.
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