Current Science

Open Access Open Access  Restricted Access Subscription Access

Contributions of Department of Biotechnology to Non-communicable Disease Biology Research in India


Affiliations
1 Medical Biotechnology Division, Human Genomics and Oncology Unit, Department of Biotechnology, Block II, CGO Complex, Lodi Road, New Delhi 110 003, India
 

The last two decades have seen a shift of focus from communicable to non-communicable diseases (NCDs). NCDs, including cancer, diabetes, cardiovascular diseases, chronic lung disease, chronic kidney disease, neurological disorders, etc., pose devastating health consequences for individuals, families and communities, and threaten health systems. The socio-economic costs associated with these chronic diseases make their control a global priority. The Department of Biotechnology is working to provide leadership and evidence-based actions on surveillance, prevention and control of NCDs to reduce the disease burden. The Department of Biotechnology (DBT) aims to develop and support competitive research and development (R&D) programmes and generate new programmes from basic to clinical and transla-tional research under NCD conditions. Diseases addressed in the programme include but are not limited to cancer, diabetes, hypertension, cardiovascular diseases, lung diseases, kidney disorders, autoimmune disorders, eye diseases, osteoporosis and bone biology, diseases of the gastrointestinal system, neurological disorders, etc. This article summarizes the contributions of DBT to NCD biology research in India through finan-cial support.

Keywords

Bio-banks, Cohort Study, Funding Agency, Non-communicable Diseases, Partnership Centres
User
Notifications
Font Size

  • Schmidt, H. et al., Chronic disease prevention and health promo-tion. In Public Health Ethics: Cases Spanning the Globe, 2016; https://pubmed.ncbi.nlm.nih.gov/28590691/

  • World Health Organization, Non-communicable diseases. 2022; https://www.who.int/news-room/fact-sheets/detail/noncommunica-ble-diseases

  • Hajata, C. and Stein, S., The global burden of multiple chronic conditions: a narrative review. Prev. Med. Rep., 2018, 12, 284–293.

  • Arokiasamy, P., India’s escalating burden of non-communicable diseases. Lancet Global Health, 2018, 12(6), e1262–e1263.

  • Yadav, A. et al., APOL1 risk allele variants are absent in Indian pa-tients with chronic kidney disease. Kidney Int., 2016, 90(4), 906–907.

  • Kumar, V. et al., Indian chronic kidney disease study: design and methods. Nephrology, 2017, 22(4), 273–278.

  • Kumar, V. et al., Existing creatinine-based equations overestimate glomerular filtration rate in Indians. BMC Nephrol., 2018, 19(22).

  • de Pinho, N. A. et al., The International Network of Chronic Kid-ney Disease cohort studies (iNET-CKD). International variations in blood pressure control and antihypertensive prescription patterns in chronic kidney disease. Kidney Int., 2019, 96(4), 983–994.

  • Orlando, P. F. et al., Collaborative, individual-level analysis com-pared longitudinal outcomes across the International Network of Chronic Kidney Disease (iNETCKD) cohorts. Kidney Int., 2019, 96(5), 1217–1233.

  • Modi, G. K. et al., Nonmedical factors and health-related quality of life in CKD in India. Clin. J. Am. Soc. Nephrol., 2020, 15(2), 191–199.

  • Prasad, N. et al., Prescription practices in patients with mild to moderate CKD in India. Kidney Int. Rep., 2021, 6(9), 2455–2462.

  • Kumar, V. et al., The Indian Chronic Kidney Disease (ICKD) study: baseline characteristics. Clin. Kidney J., 2021, 15(1), 60–69.

  • Shenoy, S. R. and Dey, B., Funding for cancer research by an Indian funding agency, DBT. J. Biosci., 2021, 46(2).

  • Mishra, N. et al., Insulin signaling pathway protects neuronal cell lines by Sirt3 mediated IRS2 activation. BioFactors, 2018, 44(3), 224–236.

  • Singh, R., Baby, R. and Suri, A., A virtual repository of neurosur-gical instrumentation for neuroengineering research and collabora-tion. World Neurosurg., 2019, 126, e84–e93.

  • Singh, R. and Suri, A., 3D printed ergonomically improved micro-forceps for microneurosurgery. World Neurosurg., 2020, 141, e271–e277.


Abstract Views: 333

PDF Views: 168




  • Contributions of Department of Biotechnology to Non-communicable Disease Biology Research in India

Abstract Views: 333  |  PDF Views: 168

Authors

Sandhya R. Shenoy
Medical Biotechnology Division, Human Genomics and Oncology Unit, Department of Biotechnology, Block II, CGO Complex, Lodi Road, New Delhi 110 003, India

Abstract


The last two decades have seen a shift of focus from communicable to non-communicable diseases (NCDs). NCDs, including cancer, diabetes, cardiovascular diseases, chronic lung disease, chronic kidney disease, neurological disorders, etc., pose devastating health consequences for individuals, families and communities, and threaten health systems. The socio-economic costs associated with these chronic diseases make their control a global priority. The Department of Biotechnology is working to provide leadership and evidence-based actions on surveillance, prevention and control of NCDs to reduce the disease burden. The Department of Biotechnology (DBT) aims to develop and support competitive research and development (R&D) programmes and generate new programmes from basic to clinical and transla-tional research under NCD conditions. Diseases addressed in the programme include but are not limited to cancer, diabetes, hypertension, cardiovascular diseases, lung diseases, kidney disorders, autoimmune disorders, eye diseases, osteoporosis and bone biology, diseases of the gastrointestinal system, neurological disorders, etc. This article summarizes the contributions of DBT to NCD biology research in India through finan-cial support.

Keywords


Bio-banks, Cohort Study, Funding Agency, Non-communicable Diseases, Partnership Centres

References





DOI: https://doi.org/10.18520/cs%2Fv123%2Fi2%2F148-153