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Subject Selection Bias in Animal Studies


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1 Pharmacology Department, Anand Pharmacy College, Anand 388 001, India
 

Animal studies have always shown bias in selection of particular sex. Female subject numbers may be becoming substantial in clinical trials after law enforcement but sadly due to no such mandates, female animals are often left out. Because of multiple cited reasons male animals are still the preferred choice in the preclinical studies. The report highlights this issue and ways to overcome bias by suggesting steps that can be taken.
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  • Subject Selection Bias in Animal Studies

Abstract Views: 450  |  PDF Views: 131

Authors

Mihir Parikh
Pharmacology Department, Anand Pharmacy College, Anand 388 001, India

Abstract


Animal studies have always shown bias in selection of particular sex. Female subject numbers may be becoming substantial in clinical trials after law enforcement but sadly due to no such mandates, female animals are often left out. Because of multiple cited reasons male animals are still the preferred choice in the preclinical studies. The report highlights this issue and ways to overcome bias by suggesting steps that can be taken.


DOI: https://doi.org/10.18520/cs%2Fv109%2Fi4%2F678-679