Polyurethane (PU)-based pressure-sensitive adhesive (PSA) tapes are commonly used during surgery. Such devices made for biomedical applications must be biocompatible and biologically safe while in use in the human body as their ingredients may leach off of a device into an adjacent tissue and can harm the body during or after application. In the present study, various methods required for biocompatibility establishment, e.g. cytotoxicity, irritation and sensitization for a device, have been analysed and presented following suitable specifications. The study also emphasizes on the developmental and curing mechanism of biomedical adhesive tape by electron beam (e-beam) irradiation.
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