Current Science

The PDF file you selected should load here if your Web browser has a PDF reader plug-in installed (for example, a recent version of Adobe Acrobat Reader).

If you would like more information about how to print, save, and work with PDFs, Highwire Press provides a helpful Frequently Asked Questions about PDFs.

Alternatively, you can download the PDF file directly to your computer, from where it can be opened using a PDF reader. To download the PDF, click the Download link above.

Fullscreen Fullscreen Off


Micro extraction packed sorbent (MEPS) containing C8 and SCX (strong cation exchange) is employed to extract ketamine, a rave drug from fruit juices. The eluant was detected by mass spectral analysis wherein the drug was detected as a parent as well as some prominent fragment ions. The resultant MEPS-MS method proved very efficient and rapid. The mass spectrum of the eluant showed the parent ion peak (MH+) of ketamine at m/z 238 along with (MH2+) peak (30% of MH+) due to chlorine atom in the drug molecule. The daughter ions at m/z 220 and 207 were possible to be formed from the MH+ by loss of water and methylamine molecule respectively. Another daughter ion at m/z 179 was proposed to be formed by the loss of CO (28 mass units) from m/z 207 whereas m/z 125 was assigned to a chlorobenzyl cation. Based on the mode of fragmentation of drug to m/z 220 and 207 and their abundances, these ions can be used for quantitative analysis through selective reaction monitoring (SRM).

Keywords

Date Rape, Extraction, Juices, Ketamine, Mass Spectrometry, MEPS.
User
Notifications
Font Size