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Research on Antivenom and Antibacterial Potential of Various Seed Extracts


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1 Department of Medicine, VA Medical Center and The University of Iowa, Iowa City, Iowa 52242, United States
     

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Aqueous extracts of Mucanapruriens, Strychnosnux vomica and Tamarindusindica seeds were checked for the antidote properties against Daboiarusselli and Echiscarinatusvenoms by in vitro methods. Various in vitro neutralization tests like proteolytic activity, Direct and Indirect hemolysis activity of various seed extracts against Daboiarusselii and Echiscarinatus venoms were carried out and all the seed extracts were effectively neutralized the toxic effects induced by the venoms. Only Mucanapruriens seed extract also exhibited antibacterial activity against Staphylococcus aureus (7mm), Pseudomonas sp. (9 mm), E. coli (6mm), Klebsiella sp. (7mm) and Proteus sp. (9mm) by well-cut method. These results suggest that these seed extracts possess some compounds which involved in neutralizing the main toxic effects of the Daboiarusselii and Echiscarinatus venoms. Spices are the flavor of life. Throughout the world, cultures and countries utilize variety of spices for many reasons. These purposes may include enhancing flavor and preserving perishable food. Spices are defined as any dried, fragrant or aromatic vegetable or plant substance that contributes flavor in a whole, broken or ground form. Many of the spices used daily have been documented to be antimicrobial and have medicinal value as well.


Keywords

Mucanapruriens, Daboiarusselii and Echiscarinatus Neutralization, Phytocgemicals.
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  • Research on Antivenom and Antibacterial Potential of Various Seed Extracts

Abstract Views: 242  |  PDF Views: 1

Authors

Wolfgang Wüster
Department of Medicine, VA Medical Center and The University of Iowa, Iowa City, Iowa 52242, United States
Kenneth Daniel Winkel
Department of Medicine, VA Medical Center and The University of Iowa, Iowa City, Iowa 52242, United States

Abstract


Aqueous extracts of Mucanapruriens, Strychnosnux vomica and Tamarindusindica seeds were checked for the antidote properties against Daboiarusselli and Echiscarinatusvenoms by in vitro methods. Various in vitro neutralization tests like proteolytic activity, Direct and Indirect hemolysis activity of various seed extracts against Daboiarusselii and Echiscarinatus venoms were carried out and all the seed extracts were effectively neutralized the toxic effects induced by the venoms. Only Mucanapruriens seed extract also exhibited antibacterial activity against Staphylococcus aureus (7mm), Pseudomonas sp. (9 mm), E. coli (6mm), Klebsiella sp. (7mm) and Proteus sp. (9mm) by well-cut method. These results suggest that these seed extracts possess some compounds which involved in neutralizing the main toxic effects of the Daboiarusselii and Echiscarinatus venoms. Spices are the flavor of life. Throughout the world, cultures and countries utilize variety of spices for many reasons. These purposes may include enhancing flavor and preserving perishable food. Spices are defined as any dried, fragrant or aromatic vegetable or plant substance that contributes flavor in a whole, broken or ground form. Many of the spices used daily have been documented to be antimicrobial and have medicinal value as well.


Keywords


Mucanapruriens, Daboiarusselii and Echiscarinatus Neutralization, Phytocgemicals.