Intelligent Algorithms for Cell Tracking and Image Segmentation

Sensitive and accurate cell tracking system is important to cell motility studies. Recently, researchers have developed several methods for detecting and tracking the living cells. To improve the living cells tracking systems performance and accuracy, we focused on developing a novel technique for image processing. The algorithm we propose presents novel image segmentation and tracking system technique to incorporate the advantages of both Topological Alignments and snakes for more accurate tracking approach. The results demonstrate that the proposed algorithm achieves accurate tracking for detecting and analyzing the mobility of the living cells. The RMSE between the manual and the computed displacement was less than 12% on average. Where the Active Contour method gave a velocity RMSE of less than 11%, improves to less than 8% by using the novel Algorithm. We have achieved better tracking and detecting for the cells, also the ability of the system to improve the low contrast, under and over segmentation which is the most cell tracking challenge problems and responsible for lacking accuracy in cell tracking techniques.