Comparative Study of Ivermectin and Cypermethrin against Sarcoptes Scabiei in Rabbit

Background: Scabies is a contagious disease caused by microscopic mites which borrow the skin and infect all wild, domestic animals as well as human beings. Which show signs or lesion mostly on ears, eyes, abdomen, nose, and inguinal region. Objective: The aim of the present study was to compare the efficacy of single topical dose of ivermectin (1%) in cream form and topical cypermethrin (1%) in spray form per week in the rabbits against scabies. While in this study cypermethrin was used first time against Sarcoptes Scabiei. Methodology: In this study, total twelfth (12) local varieties rabbits were used by authors. In which eight (08) rabbits (04 naturally infested and 04 in contacts rabbits) were used for Sarcoptes scabiei treatment, while four (04) healthy rabbits were kept in separate group as a negative (-) control. In group A, ivermectin (1%) in cream from was used, although, in second group cypermethrin was used in spray form on a weekly base while, group C remained as such fed with food and water ad libitum and no treatment was done. Clinical and microscopic examination was done by weekly base while taking skin scraping samples. Results: Furthermore, in both groups treatment was done at the same time and same route. This study shows that cypermethrin is superior in the recovery of scabies than ivermectin. Conclusions: Therefore, it was concluded that cypermethrin animal preparation could be effective, safe, and practical treatment alternative for Scabies on weekly base until recovery. However, further studies should be performed for determination of exact therapeutic doses.