International Journal of Medical and Dental Sciences

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Dental Stem Cells


Affiliations
1 Oral Medicine and Radiology, Private Practitioner, Shimla, India
2 Prosthodontics, H P Government Dental College and Hospital, Shimla, Himachal Pradesh, India
 

While the regeneration of a lost tissue is known to mankind for several years, it is only in the recent past that research on regenerative medicine/dentistry has gained momentum and eluded the dramatic yet scientific advancements in the field of molecular biology. The growing understanding of biological concepts in the regeneration of oral/dental tissues coupled with experiments on stem cells is likely to result in a paradigm shift in the therapeutic armamentarium of dental and oral diseases culminating in an intense search for "biological solutions to biological problems." Stem cells have been successfully isolated from variety of human tissues including orofacial tissues. Mesenchymal stem cells (MSCs) are multipotent stem cells which differentiate into a variety of cell types. The potential MSCs for tooth regeneration mainly include stem cells from human exfoliated deciduous teeth (SHEDs), adult dental pulp stem cells (DPSCs), stem cells from apical part of the papilla (SCAPs), stem cells from the dental follicle (DFSCs), periodontal ligament stem cells (PDLSCs) and bone marrow derived mesenchymal stem cells (BMSCs). This review article outlines the recent progress in mesenchymal stem cells used in tooth regeneration.

Keywords

Dental Stem Cells, Tooth Engineering.
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  • Dental Stem Cells

Abstract Views: 204  |  PDF Views: 130

Authors

Neha Vashisht
Oral Medicine and Radiology, Private Practitioner, Shimla, India
Divy Vashisht
Prosthodontics, H P Government Dental College and Hospital, Shimla, Himachal Pradesh, India

Abstract


While the regeneration of a lost tissue is known to mankind for several years, it is only in the recent past that research on regenerative medicine/dentistry has gained momentum and eluded the dramatic yet scientific advancements in the field of molecular biology. The growing understanding of biological concepts in the regeneration of oral/dental tissues coupled with experiments on stem cells is likely to result in a paradigm shift in the therapeutic armamentarium of dental and oral diseases culminating in an intense search for "biological solutions to biological problems." Stem cells have been successfully isolated from variety of human tissues including orofacial tissues. Mesenchymal stem cells (MSCs) are multipotent stem cells which differentiate into a variety of cell types. The potential MSCs for tooth regeneration mainly include stem cells from human exfoliated deciduous teeth (SHEDs), adult dental pulp stem cells (DPSCs), stem cells from apical part of the papilla (SCAPs), stem cells from the dental follicle (DFSCs), periodontal ligament stem cells (PDLSCs) and bone marrow derived mesenchymal stem cells (BMSCs). This review article outlines the recent progress in mesenchymal stem cells used in tooth regeneration.

Keywords


Dental Stem Cells, Tooth Engineering.

References





DOI: https://doi.org/10.18311/ijmds%2F2014%2F80741