International Journal of Medical and Dental Sciences

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Cerebroprotein Hydrolysate: Innovation in Neurodegenerative Disorders


Affiliations
1 Pathology, MMIMSR Mullana, Ambala, Haryana, India
2 Pharmacology, MMIMSR Mullana, Ambala, Haryana, India
3 Medicine, MMIMSR Mullana, Ambala, Haryana, India
4 Physiology, MMIMSR Mullana, Ambala, Haryana, India
 

Stroke, traumatic brain injury and neurodegenerative disorders are one of the leading causes of death and disability in both developing and developed countries. A number of drugs including neurotrophic drugs are available for these disorders. Cerebroprotein hydrolysate is the latest one offering new hopes to patients suffering from these disorders. Its superiority is because of different actions which help in faster and more complete nerve repair and growth than other neurotrophic agents. It acts by multiple mechanisms viz.-regulation and improvement of the neuronal metabolism, modulation of the synaptic plasticity, promoting neuronal differentiation and protection against ischemic and neurotoxin lesion, reducing excitotoxic damage, blocking over activation of calcium dependent proteases, and scavenging free oxygen radicals. Till now no serious adversity has been reported.

Keywords

Neurodegenarative Disorders, Cerebroprotein Hydrolysate, Neurotrophic Factors, Calpain.
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  • Cerebroprotein Hydrolysate: Innovation in Neurodegenerative Disorders

Abstract Views: 292  |  PDF Views: 156

Authors

Nidhi Jain
Pathology, MMIMSR Mullana, Ambala, Haryana, India
Shailesh Yadav
Pharmacology, MMIMSR Mullana, Ambala, Haryana, India
Manoj Goyal
Pharmacology, MMIMSR Mullana, Ambala, Haryana, India
Kiran Kumar Singal
Medicine, MMIMSR Mullana, Ambala, Haryana, India
Parveen Gupta
Medicine, MMIMSR Mullana, Ambala, Haryana, India
Monika Bansal
Physiology, MMIMSR Mullana, Ambala, Haryana, India

Abstract


Stroke, traumatic brain injury and neurodegenerative disorders are one of the leading causes of death and disability in both developing and developed countries. A number of drugs including neurotrophic drugs are available for these disorders. Cerebroprotein hydrolysate is the latest one offering new hopes to patients suffering from these disorders. Its superiority is because of different actions which help in faster and more complete nerve repair and growth than other neurotrophic agents. It acts by multiple mechanisms viz.-regulation and improvement of the neuronal metabolism, modulation of the synaptic plasticity, promoting neuronal differentiation and protection against ischemic and neurotoxin lesion, reducing excitotoxic damage, blocking over activation of calcium dependent proteases, and scavenging free oxygen radicals. Till now no serious adversity has been reported.

Keywords


Neurodegenarative Disorders, Cerebroprotein Hydrolysate, Neurotrophic Factors, Calpain.

References





DOI: https://doi.org/10.18311/ijmds%2F2014%2F80742