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Malignant Mixed Germ Cell Ovarian Tumor in Pregnant Female


Affiliations
1 Government Medical College Patiala, Punjab, India
 

Ovarian germ cell tumours comprise approximately 15% to 20% of all ovarian neoplasms. In pregnant females, its incidence is very low. They arise from primordial germ cells derived from the embryonal gonad. Malignant germ cell tumours comprise less than 5% of all ovarian neoplasms. Most malignant ovarian neoplasms in pregnant women are at early stages and are associated with good prognosis both for the mother and for the neonate. Histologic subtypes and prognosis do not differ from tumors not associated with pregnancy. Careful initial surgery with adequate staging biopsies followed by combination chemotherapy can greatly improve the prognosis of these patients. We present a case of malignant mixed germ cell tumor in a pregnant female who presented with abdominal mass after delivering a normal child. Histological and biochemical tumour markers confirmed it to be malignant mixed germ cell tumor.

Keywords

Malignant Mixed Germ Cell Tumour, Choriocarcinoma, Pregnancy.
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  • Malignant Mixed Germ Cell Ovarian Tumor in Pregnant Female

Abstract Views: 189  |  PDF Views: 139

Authors

S. Kaur
Government Medical College Patiala, Punjab, India
V. K. Bodal
Government Medical College Patiala, Punjab, India
M. S. Bal
Government Medical College Patiala, Punjab, India
R. Bhagat
Government Medical College Patiala, Punjab, India
N. Gupta
Government Medical College Patiala, Punjab, India

Abstract


Ovarian germ cell tumours comprise approximately 15% to 20% of all ovarian neoplasms. In pregnant females, its incidence is very low. They arise from primordial germ cells derived from the embryonal gonad. Malignant germ cell tumours comprise less than 5% of all ovarian neoplasms. Most malignant ovarian neoplasms in pregnant women are at early stages and are associated with good prognosis both for the mother and for the neonate. Histologic subtypes and prognosis do not differ from tumors not associated with pregnancy. Careful initial surgery with adequate staging biopsies followed by combination chemotherapy can greatly improve the prognosis of these patients. We present a case of malignant mixed germ cell tumor in a pregnant female who presented with abdominal mass after delivering a normal child. Histological and biochemical tumour markers confirmed it to be malignant mixed germ cell tumor.

Keywords


Malignant Mixed Germ Cell Tumour, Choriocarcinoma, Pregnancy.



DOI: https://doi.org/10.18311/ijmds%2F2013%2F86794