The Indian Practitioner

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Correlation of Histopathological and Anatomical Changes in Placenta of Intrauterine Growth Restriction (I.U.G.R)


Affiliations
1 Dept of Obstetrics And Gynaecology, M.G.M. Medical College, Indore, Madhya Pradesh, India
2 Department of Obstetrics And Gynaecology, M.G.M. Medical College, Indore, Madhya Pradesh, India
     

   Subscribe/Renew Journal


Background: Placenta is a vital organ for maintaining pregnancy and promoting normal growth by transfer of essential nutrients between fetus and mother. Any morphological alteration of placenta affects the growth of fetus leads to intrauterine growth restriction.

Material and methods: This study was conducted in 200 patients with IUGR and 200 normal patients. Gross and histopathological features of placentas of both groups are studied, analysed by student t test and compared with chi square test. p value<.05 was considered significant.

Results: Gross features weight, thickness and calcification in study show significant increase in value(p<0.05) compared to control group and histopathology of placenta also show significant increase in syncytial knots formation, cytotrophoblastic proliferation, stromal fibrosis and calcification in comparison to control group.

Conclusion: To conclude these morphological and histopathological findings of placenta are the etiological bases of I.U.G.R.


Keywords

Placenta, I.U.G.R., Syncytial Knot, Cytotrophoblastic Proliferation.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Prabhjot Kaur, Subhash Kaushal, Kuljit Singh and Ashish Sharma. Placental weight, birth weight and fetal outcome in preeclampsia and normotensive pregnancy. International journal of plants animal and environmental sciences Oct-Dec2013; 3(4):30-34

  • Fernando Arias. Practical guide to high risk pregnancy and delivary. 2008;3/e :99-100

  • Pooja Dhabha, Ghanshyam Gupta. Placental weight and surface area in iugr cases. Innovative journal of medical and health sciences. nov-dec 2014; 4-6: 198200.

  • Aherne W, Dunnill MS. Quantitative aspects of placental structure. J Pathol Bacteriol 1966 Jan;91(1):123-39

  • Cetin I, Alvino G. Intrauterine Growth Restriction: Implications for placental metabolism and transport-A review Placenta.2009;(30):77-82

  • Althshuler G, Russell P, Ermochilla R.The placental pathology of small for gestational age infants. Am J obstet. Gynecol.1975; 121: 351-59

  • J S Nigam, V Mishra, P Singh, P A singh, S Chauhan, B Thakur. Histological study of placenta in low birth baby in india.2014;4(8):79-83.

  • Hemlata M, Pani Kumar M, Jankai M, Shankar Raddy Dudala. histopathological evaluation of placentas in IUGR pregnancies. Asian Pac J. Health Sci 2014;1(4):566-569.

  • S Kotgirwar, M Ambiye, S Athavale,V Gupta, S Trivedi. Study of Gross and Histological features of placenta in intrauterine growth retardation. J. Anat. Soc. India2011; 60(1) :37-40

  • Biswas S, Ghosh SK. Gross morphological changes of placentas associated with intrauterine growth restriction of fetuses: a case-control study. Early Human Develop 2008 jun; 84(6): 357-62.

  • Gediminas Meèëjus. Influence of placental size and gross abnormalities on intrauterine growth retardation in high-risk pregnancies. Acta medica lituanica. 2005; 12 (2): p. 14–19

  • Barker DPJ. Fetal growth restriction: A workshop report. Clin sci 1998: 95; 115-128


Abstract Views: 237

PDF Views: 2




  • Correlation of Histopathological and Anatomical Changes in Placenta of Intrauterine Growth Restriction (I.U.G.R)

Abstract Views: 237  |  PDF Views: 2

Authors

N. Shrivastava
Dept of Obstetrics And Gynaecology, M.G.M. Medical College, Indore, Madhya Pradesh, India
S. Yadav
Department of Obstetrics And Gynaecology, M.G.M. Medical College, Indore, Madhya Pradesh, India

Abstract


Background: Placenta is a vital organ for maintaining pregnancy and promoting normal growth by transfer of essential nutrients between fetus and mother. Any morphological alteration of placenta affects the growth of fetus leads to intrauterine growth restriction.

Material and methods: This study was conducted in 200 patients with IUGR and 200 normal patients. Gross and histopathological features of placentas of both groups are studied, analysed by student t test and compared with chi square test. p value<.05 was considered significant.

Results: Gross features weight, thickness and calcification in study show significant increase in value(p<0.05) compared to control group and histopathology of placenta also show significant increase in syncytial knots formation, cytotrophoblastic proliferation, stromal fibrosis and calcification in comparison to control group.

Conclusion: To conclude these morphological and histopathological findings of placenta are the etiological bases of I.U.G.R.


Keywords


Placenta, I.U.G.R., Syncytial Knot, Cytotrophoblastic Proliferation.

References