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Renal Carcinoid Tumour


Affiliations
1 Department of Surgery, Indira Gandhi Medical College, Shimla (H.P.), Pin: 171001, India
2 Indira Gandhi Medical College, Shimla, India
3 Department of Surgery, Indira Gandhi Medical College, Shimla, India
     

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Carcinoid tumours are low grade malignant neuroendocrine tumours found mainly in small intestine, lungs. However primary carcinoid tumour is not normally present in the kidneys, this being an extremely rare renal malignant neoplasm with less than 100 cases reported so far, with majority of cases being associated with horse shoe kidneys. We describe a 39 years old male who presented with complaint of pain abdomen in left lumbar region, with solid renal mass detected on Computed Tomography. We treated the patient with radical nephrectomy. Pathological examination revealed tumor cells arranged in trabeculae, anastomosing cords, nests with peripheral palisading, and in cribriform pattern. The 'tumor cells showed round to oval nuclei, stippled nuclear chromatin, inconspicuous nucleoli, indistinct cell borders and scant cytoplasm, findings consistent with carcinoid tumour. IHC was positive for synaptophysin, chromogranin, and Panck. The patient has been kept on follow up to look for any local recurrence or systemic metastasis.

Keywords

Carcinoid, Kidney, Neuro-Endocrine Tumor, Synaptophysin.
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  • Renal Carcinoid Tumour

Abstract Views: 180  |  PDF Views: 0

Authors

T. Aggarwal
Department of Surgery, Indira Gandhi Medical College, Shimla (H.P.), Pin: 171001, India
A. Malhotra
Indira Gandhi Medical College, Shimla, India
K. Mardi
Indira Gandhi Medical College, Shimla, India
S. Puri
Indira Gandhi Medical College, Shimla, India
K. Malhotra
Department of Surgery, Indira Gandhi Medical College, Shimla, India
S. Goyal
Indira Gandhi Medical College, Shimla, India

Abstract


Carcinoid tumours are low grade malignant neuroendocrine tumours found mainly in small intestine, lungs. However primary carcinoid tumour is not normally present in the kidneys, this being an extremely rare renal malignant neoplasm with less than 100 cases reported so far, with majority of cases being associated with horse shoe kidneys. We describe a 39 years old male who presented with complaint of pain abdomen in left lumbar region, with solid renal mass detected on Computed Tomography. We treated the patient with radical nephrectomy. Pathological examination revealed tumor cells arranged in trabeculae, anastomosing cords, nests with peripheral palisading, and in cribriform pattern. The 'tumor cells showed round to oval nuclei, stippled nuclear chromatin, inconspicuous nucleoli, indistinct cell borders and scant cytoplasm, findings consistent with carcinoid tumour. IHC was positive for synaptophysin, chromogranin, and Panck. The patient has been kept on follow up to look for any local recurrence or systemic metastasis.

Keywords


Carcinoid, Kidney, Neuro-Endocrine Tumor, Synaptophysin.

References