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A Case of Rheumatoid Arthritis with Eosinophilia Associated With Seroconversion


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1 Department of Medicine, Seth G.S. Medical College & KEM Hospital, Parel, Mumbai, India
     

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Eosinophilia is uncommon phenomenon in patients with rheumatoid arthritis. It either reflects active rheumatoid arthritis or drug reaction.(4) We describe a case of rheumatoid arthritis who was previously seronegative, presented with symmetrical polyarthritis . After starting treatment patient became seropositive for RF and anti-ccp antibody along with significant eosinophilia. Patient was treated as RA flare with eosinophilia and seroconversion(6) with T. Methotrexate 15mg/wk, T.HCQ 300 mg HS, NSAIDS and low dose T.prednisolone. Patient was advised to follow up with CBC,ESR,CRP, RA&Anti-CCP antibody. Follow up reports showed improvement.
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  • A Case of Rheumatoid Arthritis with Eosinophilia Associated With Seroconversion

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Authors

A. Rajadhyaksha
Department of Medicine, Seth G.S. Medical College & KEM Hospital, Parel, Mumbai, India
N. S. Sarate
Department of Medicine, Seth G.S. Medical College & KEM Hospital, Parel, Mumbai, India
Y. Kuntalwad
Department of Medicine, Seth G.S. Medical College & KEM Hospital, Parel, Mumbai, India

Abstract


Eosinophilia is uncommon phenomenon in patients with rheumatoid arthritis. It either reflects active rheumatoid arthritis or drug reaction.(4) We describe a case of rheumatoid arthritis who was previously seronegative, presented with symmetrical polyarthritis . After starting treatment patient became seropositive for RF and anti-ccp antibody along with significant eosinophilia. Patient was treated as RA flare with eosinophilia and seroconversion(6) with T. Methotrexate 15mg/wk, T.HCQ 300 mg HS, NSAIDS and low dose T.prednisolone. Patient was advised to follow up with CBC,ESR,CRP, RA&Anti-CCP antibody. Follow up reports showed improvement.