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Clinical Profile of Chronic Kidney Disease Patients:A Hospital Based Study


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1 Department of Medicine, Dr. YS Parmar Govt. Medical College, Nahan, H.P., India
     

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Introduction: Chronic kidney disease is an important non-communicable disease, which is affecting the whole world. Incidence of chronic kidney disease is increasing, affecting the health care system as well as economy of the country.

Aims and Objectives: To study the clinical profile of newly diagnosed chronic disease patients at Indira Gandhi Medical College and Hospital Shimla.

Material and Methods: This was a prospective study done over a period of one year. A total of 35 patients above the age of 18 years were included in the study. Glomerular filtration rate of every patient was calculated.. Patients with glomerular filtration rate < 90 ml/dl were divided into different stages of chronic kidney disease.

Results: Out of total 35 patients,16 patients were males and 19 patients were females. 29 patients were more than 40 years of age. Most common symptom was shortness of breath followed by generalised weakness, pedal edema, fever and chest pain. 26 of the patients had positive smoking history. Past history of hypertension was present in 19 patients and there was history of diabetes in 5 patients. 91.4% of patients were having haemoglobin <12 gm%. 26 of patients enrolled in the study were having Chronic Kidney Disease stage 5 at the time of diagnosis, others were in the stage 3 or 4 of chronic kidney disease.

Conclusion: Prevalence of chronic kidney disease is increasing. Hypertension and diabetes mellitus are two most important etiological factors. There is need of the community based programmes for the early detection and treatment of hypertension and diabetes mellitus. Early identification and appropriate treatment of chronic kidney disease is required to prevent its progression to end stage renal disease.


Keywords

Chronic Kidney Disease, Glomerular Filtration Rate, Pedal Edema, Hypertension, End Stage Renal Disease.
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  • Luft FC Baa, Baa,black sheep ,are your kidneys full? J Physiol [internet] 2003;549(pt3) 365.
  • Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL. Harrison’s Principles of Internal Medicine, 19th Edition, Mc Graw Hill 2016. Chapter 335. Chronic Kidney Disease p 181121.
  • National Kidney Foundation. K/DOQI Clinical Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification and Stratification. Am J Kidney Dis 39:S1-S266, 2002 (suppl 1)
  • Lozano R, Naghavi M, Foreman K, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2013; 380: 2095–128.
  • Singh AK, Faraf YM, Mittal BV et al. Epidemiology and risk factors of chronic kidney disease in India - results from the SEEK (Screening and Early Evaluation of Kidney Disease) study.BMC Nephrol 2013 May 28;14:114.doi:10.1186/1471-2369-14-114..
  • Rajpurkar MM, John GT, Kirpalani AL. Abraham G, Agarwal SK, Almeida AF.et al. What do you know about chronic kidney disease in India: First report of the IndianCKD Registry.BMC Nephrol 2012;13(1):10
  • Sarnak MJ, Coronado BE, Greene T et al. Cardiovascular risk factors in chronic renal insufficiency. Clinic Nephrol 2002;57:327-35.
  • Jha V. Current status of end stage renal disease care in India and Pakistan. Kidney Int Suppl.2013;3(2)157-60.
  • Van der Meer V, Wielders HPM, Gischolar_mainendorst DC et al. Chronic Kidney Disease in patients with diabetes mellitus type 2 or hypertension in general practice. The British Journal of General Practice. 2010;60(581):884-890. doi:10.3399/bjgp 10X544041.
  • Ashvani Pathak,Lalit Jain,Parveen Jaiswal. To study the clinical profile of chronic kidney disease and associated comorbidities in geriatric patients. Int J Res Med Sci 2016Jul;4(7):3002-3008.
  • Amoaka YA, Laryea DO, Bedu-Addo G,Andoh H, Awuku YA. Clinical and demographic characteristics of Chronic Kidney Disease patient.in a tertiary facility in Ghana. The Pan African Medical Journal.2014;18:274.doi ;10.11604/pamj.2014.4192.
  • Stauffer ME, Fan T (2014). Prevalence of anemia in chronic kidney disease in United States. PLOS ONE 9(1): e84943.http://doi.org/10.1371/journal .prone.0084943.
  • Lewington S, Whitlock G, Clarke R et al. Blood cholestrol and vascular mortality by age, sex, and blood pressure:a metasnalysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet 2007;370:1829-39.
  • Kawagishi T, Nishzjawa Y, Konishi T, Kawasaki K, Emoto M, Shoji T et al High resolution B mode ultrasonography in evaluation of atherosclerosis in uremia.Kidney Int 1995;48:820-6.
  • Attman PO, Alaupovic P,Tavella M, Knight -Gibson C,Abnormal lipid and apolipoprotin composition of major lipoprotein density classes in patients with chronic renal failure.Nephrol dial transplant 1996;11:63-9.
  • Preston E, Ellis MR,Kulinskaya E, Davies AH, Brown EA. Association between carotid artery intima media thickness and cardiovascular risk factors in CKD. Am J Kidney Dis.2005;46:856-62.
  • Ulsi II, Ijoma CK. The Enormity of Chronic Kidney Disease in Nigeria: The Situation in a Teaching Hospital in South-East Nigeria. J Trop Med .2010 Jun;2010:501957.
  • Kaliya M, Rathod M,Gohel A. A study of clinical profile of chronic renal failure patients in tertiary care hospital. Int J of Nursing and Medical Science 2015;4(3),411-418.

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  • Clinical Profile of Chronic Kidney Disease Patients:A Hospital Based Study

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Authors

V. K. Kaushik
Department of Medicine, Dr. YS Parmar Govt. Medical College, Nahan, H.P., India
S. Chand
Department of Medicine, Dr. YS Parmar Govt. Medical College, Nahan, H.P., India
P. Agarwal
Department of Medicine, Dr. YS Parmar Govt. Medical College, Nahan, H.P., India

Abstract


Introduction: Chronic kidney disease is an important non-communicable disease, which is affecting the whole world. Incidence of chronic kidney disease is increasing, affecting the health care system as well as economy of the country.

Aims and Objectives: To study the clinical profile of newly diagnosed chronic disease patients at Indira Gandhi Medical College and Hospital Shimla.

Material and Methods: This was a prospective study done over a period of one year. A total of 35 patients above the age of 18 years were included in the study. Glomerular filtration rate of every patient was calculated.. Patients with glomerular filtration rate < 90 ml/dl were divided into different stages of chronic kidney disease.

Results: Out of total 35 patients,16 patients were males and 19 patients were females. 29 patients were more than 40 years of age. Most common symptom was shortness of breath followed by generalised weakness, pedal edema, fever and chest pain. 26 of the patients had positive smoking history. Past history of hypertension was present in 19 patients and there was history of diabetes in 5 patients. 91.4% of patients were having haemoglobin <12 gm%. 26 of patients enrolled in the study were having Chronic Kidney Disease stage 5 at the time of diagnosis, others were in the stage 3 or 4 of chronic kidney disease.

Conclusion: Prevalence of chronic kidney disease is increasing. Hypertension and diabetes mellitus are two most important etiological factors. There is need of the community based programmes for the early detection and treatment of hypertension and diabetes mellitus. Early identification and appropriate treatment of chronic kidney disease is required to prevent its progression to end stage renal disease.


Keywords


Chronic Kidney Disease, Glomerular Filtration Rate, Pedal Edema, Hypertension, End Stage Renal Disease.

References