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Neonatal Seizure:A Clinical Riddle for the Physician


Affiliations
1 Junior Resident, Department of Paediatrics, Midnapore Medical College, Vidyasagar Road, Midnapore, Paschim Medinipur-721101, West Bengal, India
2 Associate Professor, Department of Paediatrics, Midnapore Medical College, Vidyasagar Road, Midnapore, Paschim Medinipur-721101, West Bengal, India
     

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Aim: Neonatal seizures are less likely to be idiopathic. Proper diagnosis of etiology can help in prompt management. The study was done to diagnose the preventable causes early and develop strategies for the prevention of neonatal seizures.

Materials and Methods: This prospective observational study was done among neonates who developed seizures before or during the stay in the Neonatal Intensive Care Unit (NICU), irrespective of gestational age and birth weight from June 2018 to May 2019.

Results: In the study, 4.95% of the total admitted babies were with seizure out of which 66.2% were term. Most of the seizures were detected within 24 hours of birth (53.6%) in neonates of primigravida (62%) and who are delivered normally (74.7%). Present study showed subtle seizures- 45.1%, multifocal clonic seizures - 39.4%, focal clonic seizures - 8.5% and tonic seizure - 7% of cases (n = 71). Birth asphyxia (49.5%) being the most common cause followed by sepsis (29.5%) and metabolic abnormalities (25.4%). Most of the patients required only phenobarbitone (80.28%), a few patients required more than one anticonvulsant.

Conclusion: Neonatal seizures have an impact on cognitive, behavioural or epileptic complications later in life. The commonest cause of neonatal seizures is perinatal asphyxia.


Keywords

Neonatal Seizure, Etiology, Type, Ultrasound Findings.
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  • Neonatal Seizure:A Clinical Riddle for the Physician

Abstract Views: 297  |  PDF Views: 1

Authors

Sumon Mondal
Junior Resident, Department of Paediatrics, Midnapore Medical College, Vidyasagar Road, Midnapore, Paschim Medinipur-721101, West Bengal, India
Bidyut Kumar Khuntdar
Associate Professor, Department of Paediatrics, Midnapore Medical College, Vidyasagar Road, Midnapore, Paschim Medinipur-721101, West Bengal, India

Abstract


Aim: Neonatal seizures are less likely to be idiopathic. Proper diagnosis of etiology can help in prompt management. The study was done to diagnose the preventable causes early and develop strategies for the prevention of neonatal seizures.

Materials and Methods: This prospective observational study was done among neonates who developed seizures before or during the stay in the Neonatal Intensive Care Unit (NICU), irrespective of gestational age and birth weight from June 2018 to May 2019.

Results: In the study, 4.95% of the total admitted babies were with seizure out of which 66.2% were term. Most of the seizures were detected within 24 hours of birth (53.6%) in neonates of primigravida (62%) and who are delivered normally (74.7%). Present study showed subtle seizures- 45.1%, multifocal clonic seizures - 39.4%, focal clonic seizures - 8.5% and tonic seizure - 7% of cases (n = 71). Birth asphyxia (49.5%) being the most common cause followed by sepsis (29.5%) and metabolic abnormalities (25.4%). Most of the patients required only phenobarbitone (80.28%), a few patients required more than one anticonvulsant.

Conclusion: Neonatal seizures have an impact on cognitive, behavioural or epileptic complications later in life. The commonest cause of neonatal seizures is perinatal asphyxia.


Keywords


Neonatal Seizure, Etiology, Type, Ultrasound Findings.

References