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Bone Mineral Density of Post-Menopausal Diabetic and Non-Diabetic Women from Mumbai City


Affiliations
1 Department of Food Nutrition and Dietetics, Sir Vithaldas Thackersey College of Home Science (Autonomous), SNDT Women’s University, Mumbai, India
2 Sir Vithaldas Thackersey College of Home Science (Autonomous), SNDT Women’s University, Mumbai, India
3 Department Nutrition Research and Biostatistics, NutriCanvas, Mumbai, India
4 Department of Imaging Nanavati Super speciality Hospital, Mumbai, India
     

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Objective: To assess the bone mineral density of type 1 and type 2 diabetic and non-diabetic post-menopausal women.

Methods: A cross-sectional study was conducted in 98 post-menopausal women aged 60.5±6.4 years. The participants comprised of 20 type 1 diabetics, 28 type 2 diabetic women and 50 non diabetic women. Anthropometry and dietary intake was assessed for all participants. T score for bone mineral density was measured by DEXA at lumbar spine, femoral neck and total body. This was used to classify women as suffering from osteoporosis and osteopenia.

Results: The mean weight was significantly higher in type 1 and type 2 diabetics as compared to non-diabetics (p<0.05). Protein and calcium intake was 52-60% of the RDA in diabetics. There was no significant difference in T score at lumbar spine, femoral neck or total body between the 3 groups (p>0.05). After adjusting for weight and nutri-ent intake, lumbar spine and femoral neck T score was significantly lower in type 1 diabetics (p<0.05). Type 2 diabetics also had significantly lower adjusted femoral neck T score as compared to non-diabetics (p<0.05). Higher percentage of type 2 diabetics (77.8%) and non-diabetics (77.5%) had low bone density (osteopenia + osteoporosis) at lumbar spine as compared to type 1 diabetics (60%). Higher percentage of type 1 diabetics (75%) and type 2 diabetics (82.1%) had low bone density at femoral neck.

Conclusion: A high percentage of postmenopausal women in Mumbai were observed to be osteopenic and osteopo-rotic. Dietary and lifestyle Intervention programs need to be developed to prevent onset of osteopenia and osteoporo-sis especially in diabetic post-menopausal women.


Keywords

Osteoporosis, Osteopenia, Type 1 Diabetes, Type 2 Diabetes, T Score, Dietary Intake.
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  • Bone Mineral Density of Post-Menopausal Diabetic and Non-Diabetic Women from Mumbai City

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Authors

Jagmeet Madan
Department of Food Nutrition and Dietetics, Sir Vithaldas Thackersey College of Home Science (Autonomous), SNDT Women’s University, Mumbai, India
Shiza Khan
Sir Vithaldas Thackersey College of Home Science (Autonomous), SNDT Women’s University, Mumbai, India
Afshan Hussain
Sir Vithaldas Thackersey College of Home Science (Autonomous), SNDT Women’s University, Mumbai, India
Neha Sanwalka
Department Nutrition Research and Biostatistics, NutriCanvas, Mumbai, India
Deepak Patkar
Department of Imaging Nanavati Super speciality Hospital, Mumbai, India

Abstract


Objective: To assess the bone mineral density of type 1 and type 2 diabetic and non-diabetic post-menopausal women.

Methods: A cross-sectional study was conducted in 98 post-menopausal women aged 60.5±6.4 years. The participants comprised of 20 type 1 diabetics, 28 type 2 diabetic women and 50 non diabetic women. Anthropometry and dietary intake was assessed for all participants. T score for bone mineral density was measured by DEXA at lumbar spine, femoral neck and total body. This was used to classify women as suffering from osteoporosis and osteopenia.

Results: The mean weight was significantly higher in type 1 and type 2 diabetics as compared to non-diabetics (p<0.05). Protein and calcium intake was 52-60% of the RDA in diabetics. There was no significant difference in T score at lumbar spine, femoral neck or total body between the 3 groups (p>0.05). After adjusting for weight and nutri-ent intake, lumbar spine and femoral neck T score was significantly lower in type 1 diabetics (p<0.05). Type 2 diabetics also had significantly lower adjusted femoral neck T score as compared to non-diabetics (p<0.05). Higher percentage of type 2 diabetics (77.8%) and non-diabetics (77.5%) had low bone density (osteopenia + osteoporosis) at lumbar spine as compared to type 1 diabetics (60%). Higher percentage of type 1 diabetics (75%) and type 2 diabetics (82.1%) had low bone density at femoral neck.

Conclusion: A high percentage of postmenopausal women in Mumbai were observed to be osteopenic and osteopo-rotic. Dietary and lifestyle Intervention programs need to be developed to prevent onset of osteopenia and osteoporo-sis especially in diabetic post-menopausal women.


Keywords


Osteoporosis, Osteopenia, Type 1 Diabetes, Type 2 Diabetes, T Score, Dietary Intake.

References