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A Review of Gastrointestinal Aspects of COVID-19 Disease


Affiliations
1 Dept. Of Medical Gastroenterology, SVPIMSR, Smt. NHL MMC, Ahmedabad, India
2 D.M. Medical Gastroenterology, SVPIMSR and Smt. NHL MMC, Ahmedabad, India
     

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The novel coronavirus disease 2019 (COVID-19) is currently causing a major pandemic. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the Betacoronavirus genus that also includes the SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). While patients typically present with fever and a respiratory illness, some patients also report gastrointestinal symptoms such as anorexia, diar-rhoea, vomiting and abdominal pain. Studies have identified the SARS-CoV-2 RNA in stool specimens of infected patients, and its viral receptor angiotensin converting enzyme 2 (ACE2) was found to be highly expressed in gastrointestinal tract. This has important implications to the disease management, transmission, and infection con-trol. In this article, we review the important gastrointestinal aspects of the disease.

Keywords

COVID-19, ACE2 Receptor, Hepatitis, IBD, Endoscopy.
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  • A Review of Gastrointestinal Aspects of COVID-19 Disease

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Authors

Kaushal Y. Vyas
Dept. Of Medical Gastroenterology, SVPIMSR, Smt. NHL MMC, Ahmedabad, India
Jigar K. Patel
D.M. Medical Gastroenterology, SVPIMSR and Smt. NHL MMC, Ahmedabad, India

Abstract


The novel coronavirus disease 2019 (COVID-19) is currently causing a major pandemic. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a member of the Betacoronavirus genus that also includes the SARS-CoV and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). While patients typically present with fever and a respiratory illness, some patients also report gastrointestinal symptoms such as anorexia, diar-rhoea, vomiting and abdominal pain. Studies have identified the SARS-CoV-2 RNA in stool specimens of infected patients, and its viral receptor angiotensin converting enzyme 2 (ACE2) was found to be highly expressed in gastrointestinal tract. This has important implications to the disease management, transmission, and infection con-trol. In this article, we review the important gastrointestinal aspects of the disease.

Keywords


COVID-19, ACE2 Receptor, Hepatitis, IBD, Endoscopy.

References