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A Case of Dual Primary Gastric and Colonic Malignancy


Affiliations
1 Professor, Department of Gastroenterology IGMC- Shimla, India
2 Assistant Professor, Department of Gastroenterology, IGMC - Shimla, India
3 Associate Professor, Department of Gastroenterology, IGMC- Shimla, India
4 Senior Resident, Department of Gastroenterology, IGMC- Shimla, India
     

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Incidence of multiple primary malignant neoplasm increases with age, mainly because of an improvement in diagnostic techniques and prolonged survival of patients treated for malignancy. Multiple tumors may develop synchronously or metachronously. If the time interval between the appearances of the two neoplasms is less than 6 months, they are defined as synchronous, and if the time interval is longer than 6 months, they are classified as metachronous. Gastric cancer associated with synchronous colon cancer is very rare. We report a case of 56 year old male who was presented with dyspepsia with associated alarm feature and during evaluation was found to have synchronous primary gastric and colonic cancer.

Keywords

Esophagogastorduodenoscopy, Gastric Cancer, Double Primary Gastric and Colorectal Cancer, Histopathological Examination.
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  • Watanabe S et al. Multiple primary cancers in 5,456 autopsy cases in the National Cancer Center of Japan. J Natl Cancer Inst 1984; 72(5): 1021−7.

  • Billroth T. Die allgemeine chirurgische pathologie und therapie. In: Reimer G. (ed.) 14 Aufl. Berlin 1889; 908

  • Warren S, Gates O. Multiple primary malignant tumors: a survey of the literature and statistical study. Am J Cancer. 1932; 16:1358–1414.

  • Ha TK, An JY, Youn HG, et al. Surgical outcome of synchronous second primary cancer in patients with gastric cancer. Yonsei Med J 2007; 48: 981-987.

  • Yano K, Yamashita T, Chishiki M, Osaki T, Sugio K, Yasumoto K. Two cases of synchronous superficial double cancers in the esophagus and stomach. J UOEH 2002. 24: 225-232.

  • Onoue S, Katoh T, Chigira H, et al. Synchronous multiple primary cancers of the stomach and duodenum in aged patients: report of two cases. Sur Today 2000; 30: 735-738.

  • Dinis-RM, Lomba VH, Silva R, Moreira L, Lomba VR. Associated primary tumours in patients with gastric cancer. J Clin Gastroenterol 2002; 34: 533-535.

  • Mitsugu Kochi, Masashi Fujii, Noriaki Kanamori, Yoshiaki Mihara, Tomoya Funada, Hidenori Tamegai, Megumu Watanabe, Yuriko, Takayama, Hiroshi Suda, Tadatoshi Takayama. Metachronous Double Primary Gastric and Colorectal Cancer: Is Prognosis Better with Gastric or Colorectal Cancer Occurring First? Journal of Cancer Therapy, 2013, 4, 720-725

  • Green PH, O’Toole KM, Weinberg LM, Goldfarb JP. Early gastric cancer. Gastroenterology. 1981; 81:247–256.

  • Ikeguchi M, Ohfuji S, Oka A, Tsujitani S, Maeda M, Kaibara N. Synchronous and metachronous primary malignancies in organs other than the stomach in patients with early gastric cancer. Hepatogastroenterology. 1995;42:672–676

  • Bozzetti F, Bonfanti G, Mariani L, Miceli R, Andreola S. Early gastric cancer: unrecognized indicator of multiple malignancies. World J Surg. 2000; 24:583–587.

  • Ikeda Y, Saku M, Kawanaka H, Nonaka M, Yoshida K. Features of second primary cancer in patients with gastric cancer. Oncology. 2003; 65:113–117.

  • Knekt P et al. Risk of colorectal and other gastro-intestinal cancers after exposure to nitrate, nitrite and N-nitroso compounds: a follow-up study. Int J Cancer. 1999; 80:852-6.


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  • A Case of Dual Primary Gastric and Colonic Malignancy

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Authors

Brij Sharma
Professor, Department of Gastroenterology IGMC- Shimla, India
Vishal Bodh
Assistant Professor, Department of Gastroenterology, IGMC - Shimla, India
Rajesh Sharma
Associate Professor, Department of Gastroenterology, IGMC- Shimla, India
Rajesh Kumar
Senior Resident, Department of Gastroenterology, IGMC- Shimla, India

Abstract


Incidence of multiple primary malignant neoplasm increases with age, mainly because of an improvement in diagnostic techniques and prolonged survival of patients treated for malignancy. Multiple tumors may develop synchronously or metachronously. If the time interval between the appearances of the two neoplasms is less than 6 months, they are defined as synchronous, and if the time interval is longer than 6 months, they are classified as metachronous. Gastric cancer associated with synchronous colon cancer is very rare. We report a case of 56 year old male who was presented with dyspepsia with associated alarm feature and during evaluation was found to have synchronous primary gastric and colonic cancer.

Keywords


Esophagogastorduodenoscopy, Gastric Cancer, Double Primary Gastric and Colorectal Cancer, Histopathological Examination.

References