The Indian Practitioner

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

Splenomegaly - A Diagnostic Dilemma


Affiliations
1 Department of Medicine, Bharati Vidyapeeth Hospital and Research Centre, Pune, Maharashtra, India
     

   Subscribe/Renew Journal


Splenic marginal zone lymphoma is a rare form of malignant neoplasm, a subtype of Non-Hodgkin’s Lymphoma. It is usually present in middle age group with unexplained splenomegaly, abdominal pain, fatigue and weight loss. It is also known as Primary Splenic Lymphoma. Splenectomy is usually chosen as a mode for both diagnosis and treatment. Here we present a case of a 37 years old female with massive splenomegaly who was later diagnosed to have primary splenic lymphoma.

Keywords

Splenomegaly, Primary splenic lymphoma, Non-Hodgkin’s Lymphoma.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Vakil R, Golwalla A. Clinical Diagnosis, textbook of physical signs and symptoms for medical students and practitioners. 15th ed. India: Media promoters and publishers pvt. ltd; 2015. p. 410-412.

  • Kraemer BB, Osborne BM, Butler JJ. Primary splenic presentation of malignant lymphoma and related disorders. A study of 49 cases. Cancer. 1984 Oct 15;54(8):1606-19.

  • Swerdlow S, Campo E, Harris N, Jaffe E, Pileri S, Stein H, Thiele J, Arber D, Hasserjian R, Le Beau M, Orazi A, Seibert R. WHO Classification Of Tumors of Hematopoietic and Lymphoid Tissues. 4th ed. 2017. p. 185-187.

  • Camacho FI, Mollejo M, Mateo MS, Algara P, Navas C, Hernández JM, Santoja C, Solé F, Sánchez-Beato M, Piris MA. Progression to large B-cell lymphoma in splenic marginal zone lymphoma: a description of a series of 12 cases. The American Journal of Surgical Pathology. 2001 Oct 1;25(10):1268-76.

  • Gao X, Li J, Lin J, Liu D, Yu L, Wang Q. High-grade transformation in a splenic marginal zone lymphoma with a cerebral manifestation. The American Journal of Case Reports. 2017;18:611.

  • Dufresne SD, Felgar RE, Sargent RL, Surti U, Gollin SM, McPhail ED, Cook JR, Swerdlow SH. Defining the borders of splenic marginal zone lymphoma: a multiparameter study. Human Pathology. 2010 Apr 1;41(4):540-51.


Abstract Views: 267

PDF Views: 0




  • Splenomegaly - A Diagnostic Dilemma

Abstract Views: 267  |  PDF Views: 0

Authors

Aarohi Doshi
Department of Medicine, Bharati Vidyapeeth Hospital and Research Centre, Pune, Maharashtra, India
Rishi Patel
Department of Medicine, Bharati Vidyapeeth Hospital and Research Centre, Pune, Maharashtra, India
Purwa Doke
Department of Medicine, Bharati Vidyapeeth Hospital and Research Centre, Pune, Maharashtra, India

Abstract


Splenic marginal zone lymphoma is a rare form of malignant neoplasm, a subtype of Non-Hodgkin’s Lymphoma. It is usually present in middle age group with unexplained splenomegaly, abdominal pain, fatigue and weight loss. It is also known as Primary Splenic Lymphoma. Splenectomy is usually chosen as a mode for both diagnosis and treatment. Here we present a case of a 37 years old female with massive splenomegaly who was later diagnosed to have primary splenic lymphoma.

Keywords


Splenomegaly, Primary splenic lymphoma, Non-Hodgkin’s Lymphoma.

References