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Fighting Fungi
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Fungi are one of the major Kingdoms on this planet which, like all other life forms, ‘adapt to survive’. The human-fungus interaction is vast, with mycology being a major subset of microbiology and infectious diseases. This article attempts to be a neutral perspective: it not only describes how we fight off fungal infections by preventive and curative methods, but also how the fungi fight for survival in the available habitat that is largely controlled by humans. Two diseases are focused on, ringworm and mucormycosis. While the former is a troublemaker since time immemorial, mucormycosis has recently taken the limelight as an opportunistic infection in COVID-19 patients. The direct increase in the population of immunocompromised individuals is this pandemic may be due to an intensive use of steroids for treatment. The article also emphasises the need for early detection by a comprehensive diagnostic intervention (histopathology, direct microscopic examination, culture, (1,3)-β-D-glucan, galactomannan, and PCR-based assays) to ensure effective treatments and also highlights the preventive measures which can be taken to save lives. It is prudent to know the risk factors, the types of invasive mycosis, the strengths and limitations of diagnostic methods, clinical settings, and the need for standard or individualized treatment for mucormycosis in COVID-19 patients
Keywords
Fungus, tinea, ringworm, mucormycetes, mucormycosis, black fungus
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- Fungus, Merriam-Webster Dictionary [Internet], © 2021 Merriam-Webster, Incorporated. 2021 May 20. [cited 2021 June 15] Available from: https://www.merriam-webster. com/dictionary/fungus
- Ringworm (body), Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases (NCEZID), Division of Foodborne, Waterborne, and Environmental Diseases (DFWED) [Internet]. 2021 Feb 26. [cited 2021 June 15] Available from: https://www.cdc.gov/fungal/diseases/ringworm/definition. html
- Ringworm (body), Mayo Clinic [Internet], © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). 2019 Sep 13. [cited 2021 June 15]. Available from: https:// www.mayoclinic.org/diseases-conditions/ringworm-body/ symptoms-causes/syc-20353780
- Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, Schaufele RL, et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis. 2005 Sep 1;41(5):634-53.
- Mucormycosis, Fungal Diseases, Centers for Disease Control and Prevention [Internet]. 2021 Jan 14. [cited 2021 June 15]. Available from: https://www.cdc.gov/fungal/diseases/mucormycosis/definition.html
- Song G, Liang G, Liu W. Fungal co-infections associated with global COVID-19 pandemic: a clinical and diagnostic perspective from China. Mycopathologia. 2020 Jul 31:1-8.
- Guidelines for handling the Mucormycosis cases, Commisioner Health Services and Mission Director, National Health Mission, Maharashtra, Mumbai. Circular no. 11327-527/2021 dated 18.05.2021.
- Mucormycosis, Fungal Diseases, Centers for Disease Control and Prevention [Internet]. 2019 May 28. [cited 2021 June 15]. Available from: https://www.cdc.gov/fungal/diseases/mucormycosis/risk-prevention.html
- Lederberg J. Infectious history. Science. 2000 Apr 14;288(5464):287-93.
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