Covid Pneumonia in a Female with Metabolic Syndrome – A Case Report
Subscribe/Renew Journal
Evidence across the globe indicates that among patients with confirmed SARS-CoV-2 infection, the outcomes were severe in those with diabetes, obesity, and hypertension with a high incidence of mortality regardless of age. We came across a 43-year-old obese female with type 2 diabetes and hypertension diagnosed with SARS-CoV2 infection. She presented with fever and cough for the previous 3-5 days and subsequently developed breathlessness. Laboratory investigations and radiological findings confirmed the diagnosis of SARS-CoV-2 infection. Our patient had dyspnea and higher CRP, NLR, and LDH than these threshold values with a CTSS of 17 and SpO2 <71%. Moreover, the patient was previously diagnosed with metabolic syndrome. Considering the clinical status, she was hospitalized and managed as per COVID-19 protocol. Even though
at high-risk, the patient recovered well due to the efficient team-work and the holistic approach at our hospital.
Keywords
- Li C, Islam N, Gutierrez JP, Lacey B, Moolenaar RL, Richter P. Diabetes, obesity, hypertension and risk of severe COVID-19: a protocol for systematic review and meta-analysis. BMJ Open. 2021 Nov 26;11(11):e051711. doi: 10.1136/ bmjopen-2021-051711.
- Batista DV, Vieira CAFA, Costa TA, Lima EG. COVID-19associated euglycemic diabetic ketoacidosis in a patient with type 2 diabetes on SGLT2 inhibitor: a case report. Diabetol Int. 2020;12(3):313-316. Published 2020 Oct 28. doi:10.1007/ s13340-020-00473-3
- Clark CE, McDonagh STJ, McManus RJ. et al. COVID-19, and hypertension: risks and management. A scientific statement on behalf of the British and Irish Hypertension Society.J Hum Hypertens.2021;35:304–307. https://doi.org/10.1038/ s41371-020-00451-x
- Gentilotti E, Savoldi A, Compri M. et al. Assessment of COVID-19 progression on day 5 from symptoms onset.BMC Infect Dis.2021;21:883. https://doi.org/10.1186/s12879021-06596-5
- Simonnet A, Chetboun M, Poissy J, Raverdy V, Noulette J, Duhamel A, et al. High prevalence of obesity in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) requiring invasive mechanical ventilation. Obesity (Silver Spring).2020;28(7):1195–9.
- Mohammad S, Aziz R, Al Mahri S, et al. Obesity and COVID-19: what makes obese host so vulnerable?. Immun Ageing.2021;18:1. https://doi.org/10.1186/s12979-020-00212-x
- Zhu Z, Hasegawa K, Ma B, Fujiogi M, Camargo CA Jr, Liang L. Association of obesity and its genetic predisposition with the risk of severe COVID-19: Analysis of populationbased cohort data. Metabolism. 2020 Nov;112:154345. doi: 10.1016/j.metabol.2020.154345. PMID: 32835759; PMCID: PMC7442576.
- Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, et al.Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020 Apr 30;382(18):1708-1720. doi:10.1056/NEJMoa2002032.
- Zhang J, Hao Y,Ou W, et al. Serum interleukin-6 is an indicator for severity in 901 patients with SARS-CoV-2 infection: a cohort study. J Transl Med.2020;18:406. https://doi. org/10.1186/s12967-020-02571-x
- Cure E, Cure MC. Can dapagliflozin have a protective effect against COVID-19 infection? A hypothesis. Diabetes MetabSyndr. 2020;14(4):405-406.
- Bouter P. et al. Effect of epidemic influenza on ketoacidosis,pneumonia and death in diabetes mellitus: a hospital register survey of 1976-1979 in the Netherlands, Diabetes Research and Clinical Practice 1991;12:61-68.
- CDC. If you have diabetes, a flu shot could save your life. [Internet]. 2007 [2 pages]. Available from: http://www.cdc.gov/diabetes/projects/pdfs/eng-brochure.pdf.
- National Coalition for Adult Immunization round table panelists. A call to action: Improving influenza and pneumococcal immunization rates among high-risk adults (May 1998) [Internet]. 2004. Available from: http://www.nfid.org/ncai/ publications/roundtable.
- KyareMH, RoseJrCE, Fry AM, et al. The influence of chronic illnesses on the incidence of invasive pneumococcal disease in adults. J Infect Dis. 2005 Aug 1;192(3):377-386.doi:10.1086/431521.
Abstract Views: 175
PDF Views: 117