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Malignant Colo-Duodenal Fistula: A Rare Complication of Carcinoma Colon


Affiliations
1 Professor, Department of Gastroenterology, IGMC- Shimla, Himachal Pradesh, India
2 Associate Professor, Department of Gastroenterology, IGMC- Shimla, Himachal Pradesh, India
 

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Colo-duodenal fistula is a very infrequent complication of colon cancer that presents not only with severe clinical symptoms, but a poor prognosis due to locally advanced disease. It consists in a pathological communication between the lumen of the colon and duodenum. Presentation is generally sub-acute with majority of the patients presenting with non-specific abdominal pain, diarrhea, nausea and vomiting. The contact of duodenal bile salts with colonic mucosa frequently leads to diarrhea, so also duodenal colonization with colonic pathogens frequently leads to malabsorption, foul eructation and feculent vomiting. The diagnosis is established either by gastrointestinal contrast studies or contrast enhanced CT scan. Gastro-duodenoscopy and colonoscopy can demonstrate the fistulous communication and it can also be helpful in obtaining
a histological diagnosis. We report a case of a 38-year-old male patient who presented to our gastroenterology clinic with complaints of diarrhea and abdominal pain and was diagnosed to have carcinoma colon with colo-duodenal fistula.


Keywords

carcinoma colon, colo-duodenal fistula, endoscopy, colonoscopy
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  • Welch JP, Warshaw AL. Malignant duodenocolic fistulas.Am J Surg. 1977;133:658–61.
  • Calmenson M, Black BM. Surgical management of carcinoma of the right portion of the colon with secondary involvement of the duodenum, including duodenocolic fistula; data on eight cases. Surgery. 1947;21:476–81.
  • Keighley MRB, Williams NS. Intestinal fistulas. In: Surgery of the anus, rectum and colon. London: WB Saunders Co Ltd; 1993. p. 2013–2102.
  • Majeed TA, Gaurav A, Shilpa D, et al. Malignant coloduodenal fistulas-review of literature and case report. Indian J Surg Oncol. 2011;2:205–9.
  • Haldane DR. Case of cancer of the caecum, accompanied by with Caeco duodenal and Caeco colic fistulae. Edinburgh Med J. 1862;7:624–629.
  • Soulsby R, Leung E, Williams N. Malignant colo-duodenal fistula; case report and review of the literature. World Journal of Surgical Oncology. 2006;4:86.
  • Ng CK, Cheung YS, Wong CH, Li KW. Coloduodenal fistula: a rare complication of right-sided diverticulitis. Singapore Med J 2009; 50:220-222.
  • Pichney LS, Fantry GT, Graham SM. Gastrocolic and duodenocolic fistulas in Crohn’s disease. J Clin Gastroenterol.1992;15: 205-211.
  • Kamath AS, Iqbal CW, Pham TH, Wolff BG, Chua HK, et al. Management and outcomes of primary coloduodenal fistulas. J GastrointestSurg. 2011;15:1706-1711.
  • Izumi Y, Ueki T, Naritomi G, Akashi Y, Miyoshi A, Fukuda T. Malignant duodenocolic fistula: report of a case and considerations for operative management. Surg Today. 1993; 23:920–925.
  • Zer M, Wolloch Y, Lombrozo R. Palliative treatment of malignant duodenocolic fistulas. World J Surg. 1980;4:131–135.

Abstract Views: 210

PDF Views: 125




  • Malignant Colo-Duodenal Fistula: A Rare Complication of Carcinoma Colon

Abstract Views: 210  |  PDF Views: 125

Authors

Brij Sharma
Professor, Department of Gastroenterology, IGMC- Shimla, Himachal Pradesh, India
Rajesh Sharma
Associate Professor, Department of Gastroenterology, IGMC- Shimla, Himachal Pradesh, India
Vishal Bodh
Associate Professor, Department of Gastroenterology, IGMC- Shimla, Himachal Pradesh, India

Abstract


Colo-duodenal fistula is a very infrequent complication of colon cancer that presents not only with severe clinical symptoms, but a poor prognosis due to locally advanced disease. It consists in a pathological communication between the lumen of the colon and duodenum. Presentation is generally sub-acute with majority of the patients presenting with non-specific abdominal pain, diarrhea, nausea and vomiting. The contact of duodenal bile salts with colonic mucosa frequently leads to diarrhea, so also duodenal colonization with colonic pathogens frequently leads to malabsorption, foul eructation and feculent vomiting. The diagnosis is established either by gastrointestinal contrast studies or contrast enhanced CT scan. Gastro-duodenoscopy and colonoscopy can demonstrate the fistulous communication and it can also be helpful in obtaining
a histological diagnosis. We report a case of a 38-year-old male patient who presented to our gastroenterology clinic with complaints of diarrhea and abdominal pain and was diagnosed to have carcinoma colon with colo-duodenal fistula.


Keywords


carcinoma colon, colo-duodenal fistula, endoscopy, colonoscopy

References