The Indian Practitioner

Open Access Open Access  Restricted Access Subscription Access
Open Access Open Access Open Access  Restricted Access Restricted Access Subscription Access

FDG PET/CT Scan in PEComa of Lung


Affiliations
1 RSO III, Consultant Nuclear Medicine and PET CT, Bombay Hospital and Medical research Centre, 12 Marine Lines, Mumbai, Maharashtra
2 Consultant Department of Radiodiagnosis, Bombay Hospital and Medical research Centre, 12 Marine Lines, Mumbai, India
     

   Subscribe/Renew Journal


Perivascular Epithelioid Cell neoplasms (PEComa) are rare mesenchymal tumors that can occur in any part of the body and have unpredictable pathological behavior. They are usually benign but may be malignant. We present a case of benign PEComa of the lung treated with surgery. For PEComas the diagnostic criteria and treatment options have not been established however increased fluorodeoxyglucose (FDG) uptake in 18F-FDG Positron Emission Tomography/Computed Tomography (PET/CT) scan may characterize the lesion and helps in restaging prior to any treatment. Therefore, 18F-FDG PET/CT is helpful in staging and guiding treatment for PEComa with surgery or targeted therapy.

Keywords

PEComa, FDG PET, PET/CT scan, lung tumor.
Subscription Login to verify subscription
User
Notifications
Font Size


  • Tirumani SH, Shinagare AB, Hargreaves J, Jagannathan JP, Hornick JL, Wagner AJ, et al. Imaging features of primary and metastatic malignant perivascular epithelioid cell tumors. AJR Am J Roentgenol. 2014;202(2):252-8. DOI: 10.2214/ AJR.13.10909.

  • Santana AN, Nunes FS, Ho N, Takagaki TY. A rare cause of hemoptysis: Benign sugar (clear) cell tumor of the lung. Eur J Cardiothorac Surg.2004;25(4):652-4. DOI: 10.1016/j. ejcts.2004.01.022.

  • Sun L, Sun X, Li Y, Xing L. The role of (18) F‑FDG PET/CT imaging in patient with malignant PEComa treated with mTOR inhibitor. Onco Targets Ther. 2015;8:1967‑70.DOI: 10.2147/OTT.S85444.

  • Folpe AL, McKenney JK, Li Z, Smith SJ, Weiss SW. Clear cell myomelanocytic tumor of the thigh. Am J Surg Pathol. 2002;26(6):809-12. DOI: 10.1097/00000478-200206000-00018.

  • Folpe AL, Mentzel T, Lehr H-A, Fisher C, Balzer BL, Weiss SW. Perivascular epithelioid cell neoplasms of soft tissue and gynecologic origin. Am J Surg Pathol. 2005;29(12):1558- 75. DOI: 10.1097/01.pas.0000173232.22117.37.

  • Selvaggi F, Risio D, Claudi R, Cianci R, Angelucci D, Pulcini D, D’Aulerio A, Legnini M, Cotellese R, Innocenti P. Malignant PEComa: a case report with emphasis on clinical and morphological criteria. BMC Surg. 2011;11:3. DOI: 10.1186/1471-2482-11-3.


Abstract Views: 111

PDF Views: 0




  • FDG PET/CT Scan in PEComa of Lung

Abstract Views: 111  |  PDF Views: 0

Authors

Hemant Rathore
RSO III, Consultant Nuclear Medicine and PET CT, Bombay Hospital and Medical research Centre, 12 Marine Lines, Mumbai, Maharashtra
Nirav Ramesh Thaker
Consultant Department of Radiodiagnosis, Bombay Hospital and Medical research Centre, 12 Marine Lines, Mumbai, India

Abstract


Perivascular Epithelioid Cell neoplasms (PEComa) are rare mesenchymal tumors that can occur in any part of the body and have unpredictable pathological behavior. They are usually benign but may be malignant. We present a case of benign PEComa of the lung treated with surgery. For PEComas the diagnostic criteria and treatment options have not been established however increased fluorodeoxyglucose (FDG) uptake in 18F-FDG Positron Emission Tomography/Computed Tomography (PET/CT) scan may characterize the lesion and helps in restaging prior to any treatment. Therefore, 18F-FDG PET/CT is helpful in staging and guiding treatment for PEComa with surgery or targeted therapy.

Keywords


PEComa, FDG PET, PET/CT scan, lung tumor.

References