The Indian Practitioner

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Acquired Methemoglobinemia – A Case of Aniline Dye Exposure


     

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Normal hemoglobin has HbA, which is seen in 95% of the normal population and that contains iron in reduced form i.e. Fe2+. When this hemoglobin undergoes oxidation, the ferrous form Fe2+ is converted to the ferric Fe3+ state and methemoglobin is produced. The ferric state in methemoglobin renders it unable to bind to oxygen and results in a leftward shift of the oxygenhemoglobin dissociation curve. Acquired methemoglobinemia is a rare but potentially fatal disorder. We report a case of acquired methemoglobinemia that was treated as ARDS with steroids and bronchodilator therapy.

Keywords

acquired methemoglobinemia, aniline, cyanosis, dye.
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  • Acquired Methemoglobinemia – A Case of Aniline Dye Exposure

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Authors

Abstract


Normal hemoglobin has HbA, which is seen in 95% of the normal population and that contains iron in reduced form i.e. Fe2+. When this hemoglobin undergoes oxidation, the ferrous form Fe2+ is converted to the ferric Fe3+ state and methemoglobin is produced. The ferric state in methemoglobin renders it unable to bind to oxygen and results in a leftward shift of the oxygenhemoglobin dissociation curve. Acquired methemoglobinemia is a rare but potentially fatal disorder. We report a case of acquired methemoglobinemia that was treated as ARDS with steroids and bronchodilator therapy.

Keywords


acquired methemoglobinemia, aniline, cyanosis, dye.

References