The Indian Practitioner

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Newer and Future Insulins


Affiliations
1 Hospital CIMA Hermosillo. Paseo Rio San Miguel No. 35. 2do piso.Col. Proyecto Rio Sonora. Hermosillo, Sonora, Mexico
2 Investigacion Medica Sonora, S.C., Hermosillo, Sonora, Mexico
     

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The management of Diabetes was revolutionised by discovery of insulin. However the insulin delivery as well action profile of initial insulins were far from physiological. The initial insulins were replaced by recombinant insulins and later by insulin analogues.

Further refinements in insulin therapy are aimed at making these analogues more physiological, minimise risk of hypoglycaemia, making delivery timing more flexible, reduce/avoid need for injections etc.

The review summarises the recently available insulin analogues as well as few advances in the pipeline.


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  • Newer and Future Insulins

Abstract Views: 298  |  PDF Views: 1

Authors

Diego Espinoza-Peralta
Hospital CIMA Hermosillo. Paseo Rio San Miguel No. 35. 2do piso.Col. Proyecto Rio Sonora. Hermosillo, Sonora, Mexico
Jorge Rogel-Manzanares
Investigacion Medica Sonora, S.C., Hermosillo, Sonora, Mexico

Abstract


The management of Diabetes was revolutionised by discovery of insulin. However the insulin delivery as well action profile of initial insulins were far from physiological. The initial insulins were replaced by recombinant insulins and later by insulin analogues.

Further refinements in insulin therapy are aimed at making these analogues more physiological, minimise risk of hypoglycaemia, making delivery timing more flexible, reduce/avoid need for injections etc.

The review summarises the recently available insulin analogues as well as few advances in the pipeline.