Harlequin Ichthyosis Disorder

The Harlequin Ichthyosis disorder is a rare genetic condition, due to which infants are born with a thick, yellow and very hard skin. The skin has large, diamond-shaped plates separated by deep fissures, much like a fish's. Therefore, taking from the Greek word ikthys and the Latin word ichthyos, both, meaning fish. The disease has been known since 1750, and was first described in the diary of a cleric from Charleston, South Carolina.