International Journal of Medical Sciences

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Effect of High Performance Inulin (Fructo Oligosacharride) on Glycemic Control in Alloxan Induced Diabetic Rats


Affiliations
1 Krishi Vigyan Kendra (T.N.A.U.), Dharmapuri (T.N.), India
2 Home Science College and Research Institute, Tamil Nadu Agricultural University, Madurai (T.N.), India
3 PHTC, Tamil Nadu Agricultural University, Coimbatore (T.N.), India
4 Krishi Vigyan Kendra (T.N.A.U.), Thiruvarur (T.N.), India
     

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The purpose of this study was to carried out to investigate the effect of inulin extracted from Jerusalem artichoke(Helianthus tuberosis)on decrease the blood glucose in alloxan induced diabetic rats. The oral administration of inulin decreased blood glucose , implying the utility of inulin as a bioactive material to prevent metabolic diseases oh humans. In the experiment, a total of 60 white rats were completely randomly allocated into 10 groups and six rats were used in each group (54 diabetic rats and six normal rats) were used. Diabetes was induced three days before starting the experiment. Concerning growth performance, in comparison with the control group, daily weight gain in the inulin administrated rats increased and recovered to the normal level. The average weight gain in treated group ranged from 19 g (T1) to 36g (T2I) after 28 days of study period. Blood glucose was significantly lowered in the inulin administrated group from 204.16 ± 3.57 to 121.16 ± 3.4 mg/dL (a reduction of 40.65%) at the end of four weeks feeding trials.

Keywords

Inulin, Glycemic Index, Diabetic Rats.
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  • Effect of High Performance Inulin (Fructo Oligosacharride) on Glycemic Control in Alloxan Induced Diabetic Rats

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Authors

K. Jothi Lakshmi
Krishi Vigyan Kendra (T.N.A.U.), Dharmapuri (T.N.), India
M. R. Premalatha
Home Science College and Research Institute, Tamil Nadu Agricultural University, Madurai (T.N.), India
G. Gurumeenakshi
PHTC, Tamil Nadu Agricultural University, Coimbatore (T.N.), India
G. G. Kavitha Shree
Krishi Vigyan Kendra (T.N.A.U.), Thiruvarur (T.N.), India

Abstract


The purpose of this study was to carried out to investigate the effect of inulin extracted from Jerusalem artichoke(Helianthus tuberosis)on decrease the blood glucose in alloxan induced diabetic rats. The oral administration of inulin decreased blood glucose , implying the utility of inulin as a bioactive material to prevent metabolic diseases oh humans. In the experiment, a total of 60 white rats were completely randomly allocated into 10 groups and six rats were used in each group (54 diabetic rats and six normal rats) were used. Diabetes was induced three days before starting the experiment. Concerning growth performance, in comparison with the control group, daily weight gain in the inulin administrated rats increased and recovered to the normal level. The average weight gain in treated group ranged from 19 g (T1) to 36g (T2I) after 28 days of study period. Blood glucose was significantly lowered in the inulin administrated group from 204.16 ± 3.57 to 121.16 ± 3.4 mg/dL (a reduction of 40.65%) at the end of four weeks feeding trials.

Keywords


Inulin, Glycemic Index, Diabetic Rats.

References