Evaluation of Renal Function Tests in Severely Dehydrated Children with Acute Gastroenteritis with and without Hypertension

The present study was designed to determine excretion of microalbumin, total protein urea, and creatinine, and serum urea, creatinine, uric acid, sodium, and potassium in acute gastroenteritis (AGE) patients with and without hypertension. 30 children (mean age = 5.07±1.70 years) with Acute gastroenteritis with severe dehydration (fourteen boys, sixteen girls) who had history of E.coli infection, who admitted to the pediatric ward were included in the study. Age and sex-matched 30 children, not having any acute illness and renal disease were taken as control. Urinary total proteins and microalbumin were estimated by pyrogallol red method and immunoturbidimetric method, respectively. Other renal function tests were determined by commercial kit. In our study, we observed all patients were microalbuminuric and suffering from E.coli infection. The alterations of serum urea, creatinine, uric acid, sodium, potassium and also urinary urea, creatinine, total proteins levels in AGE children as compared to that of control group. We, therefore, conclude that these investigations should be performed routinely in AGE of children. Otherwise lack of appropriate and early treatment can lead to acute renal failure (ARF) or chronic renal failure (CRF).