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Nanosuspensions is an Emerging Carrier for Efficient Delivery of Hydrophobic Drugs


Affiliations
1 Anand College of Pharmacy, Agra (U.P.), India
2 Department of Pharmacy, Singhania University, Singhana (Raj.), India
3 S.D. College of Pharmacy and Vocational Studies, Muzaffarnagar (U.P.), India
     

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Nanosuspensions (Muller et al., 1995) have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. The present article describes the details about nanosuspensions. Nanosuspensions consist of the pure poorly water-soluble drug without any matrix material suspended in dispersion. The review article includes the methods of preparation with their merits and demerits, characterization and evaluation parameters. A nanosuspension not only solves the problems of poor solubility and bioavailability, but also alters the pharmacokinetics of drug and thus improves drug safety and efficacy.

Keywords

Nanosuspensions, Hydrophobic Drugs.
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  • Nanosuspensions is an Emerging Carrier for Efficient Delivery of Hydrophobic Drugs

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Authors

Zubi Aziz
Anand College of Pharmacy, Agra (U.P.), India
Rahul Raj
Department of Pharmacy, Singhania University, Singhana (Raj.), India
R. K. Nema
S.D. College of Pharmacy and Vocational Studies, Muzaffarnagar (U.P.), India

Abstract


Nanosuspensions (Muller et al., 1995) have emerged as a promising strategy for the efficient delivery of hydrophobic drugs because of their versatile features and unique advantages. The present article describes the details about nanosuspensions. Nanosuspensions consist of the pure poorly water-soluble drug without any matrix material suspended in dispersion. The review article includes the methods of preparation with their merits and demerits, characterization and evaluation parameters. A nanosuspension not only solves the problems of poor solubility and bioavailability, but also alters the pharmacokinetics of drug and thus improves drug safety and efficacy.

Keywords


Nanosuspensions, Hydrophobic Drugs.