Male Reproductive Toxic Effect of Quassia amara: Observations on Mouse Sperm

Quassia amara is a medicinal plant with several pharmacological properties. More recently, it has come to be known in the context of its potential biopesticidal application and the antimalarial property in two of its secondary metabolites, quassin and neo-quassin. There are also preliminary reports implicating this plant in male reproductive toxic effects, to the extent that the plant could as well be tested for male contraceptive efficacy. Therfore, we subjected the methanolic extract of the bark of this tree for male reproductive toxicological evaluation. This paper reports several derangements in the Cauda epididymidal sperm including a hither - to unreported one.