Molecular Aspects of Gender Specific Influence of Testosterone and Estradiol on Normal Post-Natal Development and Growth of the Thyroid Gland

Gender bias in the incidence of thyroid diseases and cancers with preponderance towards females is well known. Recent studies from our laboratory underscored the importance of sex steroids in the gender biased incidence rate and nature of thyroid cancers in human and experimental rats. Information on the importance of any factor in normal growth and function of an organ will be an important tool to propose new hypothesis on the molecular mechanism involved in the incidence and nature of cancer and congenital abnormalities.