Beneficial Effects of Some Antioxidants and Calcium for Reversal of Fluoride and Arsenic Induced Toxicity in Mice Ovary

Studies on benefical effects of some antioxidant Vitamins (C and E) and Calcium phosphate supplementation to mice for recovery in ovarian steroidogenesis after sodium fluoride (NaF 5 mg/kg body weight) and arsenic trioxide (As₂O₃ 0.5 mg/kg body weight) treatment were undertaken. The doses of toxicants were based on their LD₅₀ value while those of the vitamms and calcium on previous work. All the biochemical parameters (protein, cholesterol, 3β and 17β HSD) were studied using standard methods.