Studies on Testis Lactate Dehydrogenase in Normal, Alloxan-Induced Diabetics and Cassia Auriculata Administered Mice

Lactate dehydrogenase of testis were analyzed in normal healthy male mice. There were five LDH fraction corresponding to LDH1, LDH2, LDH3, LDH4 and LDH5. The activity of these five fracfions were 28%, 32%, 14%, 11% and 15%, respectively. In alloxan induced diabetics mice, there was remarkable change in the testis LDH pattern as well as well as its activity. There was significant increase in the number of fractions to eight. Two new fractions appeared between LDH1 and LDH2 and one fraction appeared between LDH4 and LDH5. The activity of LDH1 increased to 35%, LDH3 to 25% while those of all other fractions decreased.