Modulation of Rat Heart Superoxide Dismutase, Catalase and Lipid Peroxidation by Thyroid Hormone

The heart tissue is considered highly responsive to thyroid hormones. However, the functional aspect of cardiac mitochondria in this context is not yet fiilly elucidated. The present work for the first time attempts to highlight the possible effects of thyroid hormone on peroxidative stress in mitochondrial milieu of rat heart with respect to its primary antioxidant capacity. The antioxidant enzymes of post-mitochondrial fraction (PMF) were also investigated for comparative purpose.