Estimation of Protein and Lipid of Ceylonocotyle scoliocoelium (Trematoda) Following Administraion of Mebendazole under in vitro Condition

Mebendazole is reported as a highly elTective antihciininthic drug. This compound causes mortality of the helminth parasites. In viiro administration of mebendazole lowered the total protein content of Ceyloiwcoiyle scoliocoeliiiiii, which is a common rumen irematode of cattle. Death of the parasite after mebendazole treatment is supposed to be due to enzymatic blockage of protein synthesis or due to activation of certain proteolytic substances. No change of local lipid content is observed after mebendazole administration. Total protein and lipid of C. scoliocoeliiim were estimated in spectrophotometry. Protein bands were studied by SDS-PAGE.