Effects of Regular Exercise Training and Acute Exhaustive Exercise on Serum SOD Responses:The Possibility of Serum SOD as Health-Related Indicator

In the current study, serum SOD activity was analyzed to evaluate the effects of regular exercise training and an acute bout of exhaustive maximal exercise for the development of health related indicator analysis technology. It was hypothesized that trained men who have been participated in regular exercise training would have higher SOD activity than the untrained men, and serum SOD activity would be increased after acute exhaustive exercise by increased ROS production. 16 college-age male volunteers (21.3 ± 2.2 years) were recruited. Among them, eight was elite Taekwondo players (trained group), and they were participated in regular exercise training. Other eight was healthy untrained students (untrained group). The untrained subjects had no previously experience of regular training. All subjects were prescreened prior to being accepted as a subject. The subjects performed a maximal graded-exercise test with Bruce protocol on a treadmill ergometer. Blood samples were taken before, and immediately after, and 1 hour after exercise, and serum SOD activities were analyzed. The data were analyzed by SPSS program using two-way repeated-measures ANOVA. There was no significant group × time interaction or group effects for serum SOD activity. However, a significant time effect occurred in the change of serum SOD activity among three measurement time points (P < 0.001). Serum SOD activity after immediately after exhaustive exercise was significantly lower compared with pre-exercise and 60 minutes post exercise, independent of group (P < 0.01). In conclusion, the results of this study suggest that serum SOD activity is not the best health-related indicator to demonstrate the effect of acute and regular exercise training on antioxidant defense system.