Journal of Pharmaceutical Research

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A Review on CNS Effects of Abelmoschus moschatus


Affiliations
1 Department of Pharmacology, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Bangalore-560035, India
 

Purpose:Traditional and complementary medicine has helped discover several medicinally important herbs, understand their mechanism of action and use them as drugs to treat serious medical conditions. In the current review, the role of one such herbal extract, Abelmoschus mochatus (AM) in CNS disorders will be detailed.

Approach: Published articles from Pubmed and other sources were used to review and compile the CNS effects of AM.

Findings: AM seed extract has shown potent anti-oxidant effects leading to its protective effect in neurological disorders. In addition, it also shows antidepressant, anxiolytic, antiepileptic and sedative properties in animal models.

Conclusion: AM can be used as an adjuvant therapy in neurological and psychiatric conditions. Research into the precise mechanisms underlying the CNS effects of Abelmoschus moschatus will aid its use in myriad CNS conditions.


Keywords

Abelmoschus moschatus, Antioxidant, Parkinson's Disease, Herbal Remedies.
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  • A Review on CNS Effects of Abelmoschus moschatus

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Authors

M. Giri
Department of Pharmacology, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Bangalore-560035, India
J. Vivek
Department of Pharmacology, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Bangalore-560035, India
K. Mahati
Department of Pharmacology, Krupanidhi College of Pharmacy, Chikkabellandur, Carmelaram Post, Bangalore-560035, India

Abstract


Purpose:Traditional and complementary medicine has helped discover several medicinally important herbs, understand their mechanism of action and use them as drugs to treat serious medical conditions. In the current review, the role of one such herbal extract, Abelmoschus mochatus (AM) in CNS disorders will be detailed.

Approach: Published articles from Pubmed and other sources were used to review and compile the CNS effects of AM.

Findings: AM seed extract has shown potent anti-oxidant effects leading to its protective effect in neurological disorders. In addition, it also shows antidepressant, anxiolytic, antiepileptic and sedative properties in animal models.

Conclusion: AM can be used as an adjuvant therapy in neurological and psychiatric conditions. Research into the precise mechanisms underlying the CNS effects of Abelmoschus moschatus will aid its use in myriad CNS conditions.


Keywords


Abelmoschus moschatus, Antioxidant, Parkinson's Disease, Herbal Remedies.

References