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A Brief Review on Sustained Release Matrix Type Drug Delivery System


Affiliations
1 Department of Pharmaceutics, Krupanidhi College of Pharmacy, #12/1, Chikkabellandur, Carmelaram Post, Varthur Hobli, Bangalore - 560035, KA, India
 

Purpose: A review on sustained release drug delivery using polymer matrix with emphasis on its contemporary usage and future trends.

Approach: An introduction to sustained release drug delivery system (SR DDS), followed by its rationale, advantages, disadvantages, criteria of a drug to be met to formulate sustained release formulations, classification of matrix tablets, classification of polymers, its mechanism and recent advancements.

Finding: Recent studies indicate that sustained delivery for a very long period, in terms of months is possible using suitable polymer matrices. Also, challenging drug candidates such as proteins are now successfully delivered as sustained release dosage forms.

Conclusion: Sustained release DDS, since 1940s has evolved in different types of dosage forms for sustained effect but future scope will be to treat chronic diseases providing sustained effect.


Keywords

Sustained Release, Polymers, Recent Advancements.
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  • A Brief Review on Sustained Release Matrix Type Drug Delivery System

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Authors

Mayur Karvekar
Department of Pharmaceutics, Krupanidhi College of Pharmacy, #12/1, Chikkabellandur, Carmelaram Post, Varthur Hobli, Bangalore - 560035, KA, India
Arshad Bashir Khan
Department of Pharmaceutics, Krupanidhi College of Pharmacy, #12/1, Chikkabellandur, Carmelaram Post, Varthur Hobli, Bangalore - 560035, KA, India

Abstract


Purpose: A review on sustained release drug delivery using polymer matrix with emphasis on its contemporary usage and future trends.

Approach: An introduction to sustained release drug delivery system (SR DDS), followed by its rationale, advantages, disadvantages, criteria of a drug to be met to formulate sustained release formulations, classification of matrix tablets, classification of polymers, its mechanism and recent advancements.

Finding: Recent studies indicate that sustained delivery for a very long period, in terms of months is possible using suitable polymer matrices. Also, challenging drug candidates such as proteins are now successfully delivered as sustained release dosage forms.

Conclusion: Sustained release DDS, since 1940s has evolved in different types of dosage forms for sustained effect but future scope will be to treat chronic diseases providing sustained effect.


Keywords


Sustained Release, Polymers, Recent Advancements.

References