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Effect of Abutilon indicum on Carbon Tetrachloride Induced Hepatic Damage in Albino Rats
Ethanolic extract of Abutilon indicum (Malvaceae) was screened for its hepatoprotective potential, using carbon tetra chloride induced hepatic damage model in rats. A dose of 400 mg / kg body weight was employed in the study. The effect was assessed by monitoring the serum levels of the following enzymes, like serum glutamate-oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), serum alkaline phosphatase (SALP). Abutilon indicum significantly reduced serum levels of SGOT, SGPT, and SALP comparable with Liv-52 as a reference standard.
Keywords
Abutilon indicum, Liv-52, Ethanolic Extract, Carbon Tetrachloride.
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