Estimation of Cefditoren Pivoxil in Pharmaceutical Oral Solid Dosage form by Spectrophotometry

Four new, simple, sensitive and reproducible spectrophotometric methods have been developed for the estimation of cefditoren pivoxil in tablet dosage form. Method A involves the determination of cefditoren pivoxil by Standard absorbance method at 230nm and the Beer's concentration range was found to be 5-50 μg/mL. Method B and Method C involve the determination of cefditoren pivoxil by first derivative spectrophotometry and second derivative spectrophotometry respectively. The normal spectrum was derivatized to first and second order derivative spectrum and the linearity was found to lie within the Beer's range for cefditoren pivoxil. Method D involves the determination of cefditoren pivoxil by area under curve method and the linearity was established.