Open Access Open Access  Restricted Access Subscription Access

Antimicrobial Activity of Azomethines of Aryl Thiazole


Affiliations
1 Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai-3, India
 

Aryl thiazoles and their azomethines attract a wide spread interest due to the diversified biological activities. Five new azomethines of aryl thiazole were synthesised and the structure were assigned according to their spectral data. These compounds were screened for their antibacterial activity against both Gram positive and Gram negative organisms. The recorded zone of inhibition showed significant broad spectrum activity when compared with standard ciprofloxacin. Antifungal screening indicated that all the synthesised compounds had inhibitory effect against the tested pathogenic fungi.

Keywords

Azomethines, Thiazoles, Antimicrobial Activity.
User
Notifications
Font Size


Abstract Views: 239

PDF Views: 109




  • Antimicrobial Activity of Azomethines of Aryl Thiazole

Abstract Views: 239  |  PDF Views: 109

Authors

V. Niraimathi
Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai-3, India
A. Jerad Suresh
Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai-3, India
Latha Sriram
Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai-3, India
R. Kokila
Department of Pharmaceutical Chemistry, College of Pharmacy, Madras Medical College, Chennai-3, India

Abstract


Aryl thiazoles and their azomethines attract a wide spread interest due to the diversified biological activities. Five new azomethines of aryl thiazole were synthesised and the structure were assigned according to their spectral data. These compounds were screened for their antibacterial activity against both Gram positive and Gram negative organisms. The recorded zone of inhibition showed significant broad spectrum activity when compared with standard ciprofloxacin. Antifungal screening indicated that all the synthesised compounds had inhibitory effect against the tested pathogenic fungi.

Keywords


Azomethines, Thiazoles, Antimicrobial Activity.